PPIST05077

Protein Information
Protein_Chain A
Protein_Sequence GSDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGG
Peptide Information
Peptide_Chain B
Peptide_Sequence KALETLRRVGDGVLRNHLTAF
Peptide_Length 21
Non-standard residues No
Interaction Information
PDB_ID 3MK8
Method X-RAY DIFFRACTION
Resolution 2.32 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer.
Release_Year 2010
PMID 20562877
DOI 10.1038/nchembio.391