PPIST08129

Protein Information
Protein_Chain A;B;C;D
Protein_Sequence AQNPLVYLDVGADGQPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPAFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGKTSKKIVITDCGQLS
Peptide Information
Peptide_Chain E;F;G;H
Peptide_Sequence ALLVTAAXVLA
Peptide_Length 11
Non-standard residues Yes
Interaction Information
PDB_ID 4TOT
Method X-RAY DIFFRACTION
Resolution 2.39 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition.
Release_Year 2014
PMID 25310383
DOI 10.1021/jm500862r