PPIST17949

Protein Information
Protein_Chain A;B;C;D;E;F
Protein_Sequence PIVQNLQGQMVHQCISPRTLNAWVKVVEEKAFSPEVIPMFSALSCGATPQDLNTMLNTVGGHQAAIQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNAATETLLVQNANPDCKTILKALGPGATLEEMMTACQGVGGPGHKARVL
Peptide Information
Peptide_Chain G[auth M];H[auth N];I[auth O];J[auth P];K[auth Q];L[auth R]
Peptide_Sequence PVLFPGQPFGQPPLG
Peptide_Length 15
Non-standard residues No
Interaction Information
PDB_ID 8GDV
Method X-RAY DIFFRACTION
Resolution 3.30 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Structural and mechanistic bases for resistance of the M66I capsid variant to lenacapavir.
Release_Year 2025
PMID 40231850
DOI 10.1128/mbio.03613-24