PPIDT00014
Drug Information
| Name | Goserelin |
|---|---|
| Sequence | pEHWSYdS(tBu)LRPAzGlyNH₂ |
| DrugBank_ID | DB00014 |
| Type | small molecule |
| Indication | Goserelin is indicated for: - Use in combination with flutamide for the management of locally confined carcinoma of the prostate - Palliative treatment of advanced carcinoma of the prostate - The management of endometriosis - Use as an endometrial-thinning agent prior to endometrial ablation for dysfunctional uterine bleeding - Use in the palliative treatment of advanced breast cancer in pre- and perimenopausal women |
Dosage Forms
| Form | Route | Strength |
|---|---|---|
| Implant | — |
|
| Implant | Parenteral; Subcutaneous |
10.8 MG
|
| Implant | Parenteral; Subcutaneous |
3.6 MG
|
| Implant | Subcutaneous |
10.8 mg/1
|
| Implant | Subcutaneous |
3.6 mg
|
| Implant | Subcutaneous |
3.6 mg/1
|
| Implant | Subcutaneous |
360000 mg
|
| Implant | Subcutaneous |
1080000 mg
|
| Implant | — |
10.8 mg
|
| Implant | — |
3.6 mg
|
| Injection | Subcutaneous |
3.6 mg
|
| Implant | Subcutaneous |
10.8 mg
|
| Injection | Subcutaneous |
10.8 mg
|
| Solution | — |
3.6 mg
|
| Solution | — |
10.8 mg
|
Target Information
| Role | Uniprot_ID | Gene_Name | Entity_Name | Organism | Actions | Internal link |
|---|---|---|---|---|---|---|
| target | P22888 | LHCGR | Lutropin-choriogonadotropic hormone receptor | Homo sapiens | agonist | Link |
| target | P01148 | GNRH1 | Progonadoliberin-1 | Homo sapiens | activator | Link |
| target | P30968 | GNRHR | Gonadotropin-releasing hormone receptor | Homo sapiens | agonist | Link |