PPIDT00038
Drug Information
| Name | Aldesleukin |
|---|---|
| Sequence | MPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFSQSIISTLT |
| DrugBank_ID | DB00041 |
| Type | biotech |
| Indication | For treatment of adults with metastatic renal cell carcinoma. |
Dosage Forms
| Form | Route | Strength |
|---|---|---|
| Injection | Intravenous |
1.1 mg/1mL
|
| Injection, powder, for solution | Parenteral; Subcutaneous |
18000.000 UI/ML
|
| Injection, powder, lyophilized, for solution | Intravenous |
1.1 mg/1mL
|
| Powder, for solution | Intravenous |
22000000 unit / vial
|
| Injection, powder, for solution | Parenteral |
|
| Injection, powder, lyophilized, for solution | Intravenous |
1.1 mg/ml
|
| Injection, powder, for solution | Intravenous |
18 miu
|
Target Information
| Role | Uniprot_ID | Gene_Name | Entity_Name | Organism | Actions | Internal link |
|---|---|---|---|---|---|---|
| target | P14784 | IL2RB | Interleukin-2 receptor subunit beta | Homo sapiens | agonist|modulator | Link |
| target | P01589 | IL2RA | Interleukin-2 receptor subunit alpha | Homo sapiens | agonist|modulator | Link |
| target | P31785 | IL2RG | Cytokine receptor common subunit gamma | Homo sapiens | agonist | Link |
| enzyme | P35354 | PTGS2 | Prostaglandin G/H synthase 2 | Homo sapiens | inducer | Link |
| enzyme | P47712 | PLA2G4A | Cytosolic phospholipase A2 | Homo sapiens | inducer | Link |
| enzyme | P08684 | CYP3A4 | Cytochrome P450 3A4 | Homo sapiens | inhibitor | Link |
| enzyme | P47989 | XDH | Xanthine dehydrogenase/oxidase | Homo sapiens | inducer | Link |
| enzyme | P05181 | CYP2E1 | Cytochrome P450 2E1 | Homo sapiens | inhibitor | Link |