PPIDT00055

Drug Information
NameInfliximab
SequenceEVKLEESGGGLVQPGGSMKLSCVASGFIFSNHWMNWVRQSPEKGLEWVAEIRSKSINSATHYAESVKGRFTISRDDSKSAVYLQMTDLRTEDTGVYYCSRNYYGSTYDYWGQGTTLTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDTAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
DrugBank_IDDB00065
Typebiotech
IndicationInfliximab is indicated for the following conditions: - moderately to severely active ulcerative colitis following treatment with an infliximab product administered intravenously [L51793] - moderately to severely active Crohn’s disease following treatment with an infliximab product administered intravenously [L51793] - use in combination with methotrexate for the reduction in signs and symptoms, inhibition of the progression of structural damage and improvement in physical function in adult patients with moderately to severely active rheumatoid arthritis. • maintenance treatment of adults with moderately to severely active Crohn’s disease who have had an inadequate response or were intolerant to conventional therapy. Remsima SC should only be used as maintenance therapy after the completion of an induction period with intravenous infliximab. • maintenance treatment of adults with moderately to severely active ulcerative colitis who have had an inadequate response or were intolerant to conventional therapy. Remsima SC should only be used as maintenance therapy after the completion of an induction period with intravenous infliximab.

Dosage Forms
Form Route Strength
Powder Parenteral
100 MG
Injection, powder, for solution Intravenous; Parenteral
100 MG
Injection, powder, lyophilized, for solution Intravenous
100 mg/10mL
100 mg/1vial
Injection, powder, lyophilized, for solution Intravenous
100 mg
Powder
100 mg/1vial
Powder Intravenous; Parenteral
100 MG
Powder, for solution Intravenous
100 mg / vial
Injection, powder, lyophilized, for solution Intravenous
10000000 mg
Injection, solution, concentrate Intravenous
100 mg
Injection, powder, for solution Intravenous
100 mg
Injection, solution Parenteral; Subcutaneous
120 MG
Injection, solution Subcutaneous
120 mg
Injection, solution, concentrate Intravenous
100 mg/1vial
Solution Intravenous
100.000 mg
Injection Intravenous
100 mg
Solution
120 mg
Solution Subcutaneous
12000000 mg
Kit; solution Subcutaneous
120 mg / mL
Solution Subcutaneous
120.00 mg
Injection, solution Subcutaneous
120 mg/ml
Injection, powder, lyophilized, for suspension Intravenous
100 mg
Injection, powder, lyophilized, for solution Intravenous
100 mg/1
Injection, powder, for solution
100 mg
Injection Subcutaneous
120 mg/1mL
Target Information
Role Uniprot_ID Gene_Name Entity_Name Organism Actions Internal link
target P01375 TNF Tumor necrosis factor Homo sapiens inhibitor Link