PPIDT00069
Drug Information
| Name | Pegvisomant |
|---|---|
| Sequence | FPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF |
| DrugBank_ID | DB00082 |
| Type | biotech |
| Indication | Pegvisomant is a growth hormone receptor antagonist used for the treatment of acromegaly. |
Dosage Forms
| Form | Route | Strength |
|---|---|---|
| Injection, powder, for solution | Parenteral; Subcutaneous |
10 MG
|
| Injection, powder, for solution | Parenteral; Subcutaneous |
15 MG
|
| Injection, powder, for solution | Parenteral; Subcutaneous |
20 MG
|
| Injection, powder, for solution | Parenteral; Subcutaneous |
25 MG
|
| Injection, powder, for solution | Parenteral; Subcutaneous |
30 MG
|
| Injection, powder, for solution | Subcutaneous |
10 mg
|
| Injection, powder, for solution | Subcutaneous |
15 mg
|
| Injection, powder, for solution | Subcutaneous |
20 mg
|
| Injection, powder, for solution | Subcutaneous |
25 mg
|
| Injection, powder, for solution | Subcutaneous |
30 mg
|
| Injection, powder, lyophilized, for solution; kit | Subcutaneous |
10 mg/1mL
|
| Injection, powder, lyophilized, for solution; kit | Subcutaneous |
15 mg/1mL
|
| Injection, powder, lyophilized, for solution; kit | Subcutaneous |
20 mg/1mL
|
| Injection, powder, lyophilized, for solution; kit | Subcutaneous |
25 mg/1mL
|
| Injection, powder, lyophilized, for solution; kit | Subcutaneous |
30 mg/1mL
|
| Kit; powder, for solution | Subcutaneous |
10 mg / vial
|
| Kit; powder, for solution | Subcutaneous |
15 mg / vial
|
| Kit; powder, for solution | Subcutaneous |
20 mg / vial
|
| Kit; powder, for solution | Subcutaneous |
25 mg / vial
|
| Kit; powder, for solution | Subcutaneous |
30 mg / vial
|
| Injection, powder, lyophilized, for solution | Subcutaneous |
1000000 mg
|
| Injection, solution | — |
10 mg
|
| Injection, solution | — |
15 mg
|
| Injection, solution | — |
20 mg
|
| Injection, powder, lyophilized, for solution | Subcutaneous |
15 mg
|
| Injection, powder, lyophilized, for solution | Subcutaneous |
1500000 mg
|
Target Information
| Role | Uniprot_ID | Gene_Name | Entity_Name | Organism | Actions | Internal link |
|---|---|---|---|---|---|---|
| target | P10912 | GHR | Growth hormone receptor | Homo sapiens | antagonist | Link |
| enzyme | Q02318 | CYP27A1 | Sterol 26-hydroxylase, mitochondrial | Homo sapiens | inducer | Link |
| enzyme | P15104 | GLUL | Glutamine synthetase | Homo sapiens | inhibitor | Link |
| enzyme | P08684 | CYP3A4 | Cytochrome P450 3A4 | Homo sapiens | inducer | Link |
| enzyme | P06276 | BCHE | Cholinesterase | Homo sapiens | inhibitor | Link |
| enzyme | Q02928 | CYP4A11 | Cytochrome P450 4A11 | Homo sapiens | inhibitor | Link |