PPIDT00086
Drug Information
| Name | Oxytocin |
|---|---|
| Sequence | CYIQNCPLG |
| DrugBank_ID | DB00107 |
| Type | biotech |
| Indication | Administration of exogenous oxytocin is indicated in the antepartum period to initiate or improve uterine contractions for vaginal delivery in situations where there is fetal or maternal concern.[L31433] For example, It may be used to induce labor in cases of Rh sensitization, maternal diabetes, preeclampsia at or near term, and when delivery is indicated due to prematurely ruptured membranes.[A229018,L31433] Importantly, oxytocin is not approved or indicated for elective induction of labor. Oxytocin may be used to reinforce labor in select cases of uterine inertia and as adjunctive therapy in the management of incomplete or inevitable abortion. In the postpartum period, oxytocin may be used to induced contractions in the 3rd stage of labor and to control postpartum bleeding or hemorrhage.[L31433] |
Dosage Forms
| Form | Route | Strength |
|---|---|---|
| Liquid | Topical |
|
| Solution | Intravenous |
10.00 UI
|
| Solution | Parenteral |
5.0000 UI
|
| Injection, solution | Intramuscular; Intravenous |
5 iu/ml
|
| Injection, solution | — |
|
| Injection, solution | — |
16.7 MICROGRAMMI/ML
|
| Injection, solution | — |
8.3 MICROGRAMMI/ML
|
| Solution | Intravenous |
500000 IU
|
| Solution | Intravenous |
1000000 IU
|
| Solution | Parenteral |
1000000 IU
|
| Solution | Intramuscular; Intravenous |
1000000 IU
|
| Injection | — |
10 IU
|
| Injection | Intramuscular; Intravascular |
100 [USP'U]/10mL
|
| Injection | Intravenous |
10 [USP'U]/1mL
|
| Injection | Intravenous |
10 IUML
|
| Injection | Intravenous |
10 IU/ml
|
| Injection | Intravenous |
10 [iU]/1mL
|
| Injection | Intravenous |
100 [USP'U]/10mL
|
| Injection, solution | Intramuscular; Intravenous |
10 [USP'U]/1mL
|
| Injection, solution | Intravenous |
10 [USP'U]/1000mL
|
| Injection, solution | Intravenous |
10 [USP'U]/500mL
|
| Injection, solution | Intravenous |
2 [USP'U]/100mL
|
| Injection, solution | Intravenous |
20 [USP'U]/500mL
|
| Injection, solution | Intravenous |
20 [USP'U]/1000mL
|
| Injection, solution | Intravenous |
30 [USP'U]/1000mL
|
| Injection, solution | Intravenous |
30 [USP'U]/500mL
|
| Injection, solution | Parenteral |
|
| Liquid | Intramuscular; Intravenous |
10 unit / mL
|
| Solution | Intramuscular; Intravenous |
10 unit / mL
|
| Solution | Intramuscular; Intravenous |
10 IU/ml
|
| Injection | Intramuscular; Intravenous |
10 [USP'U]/1mL
|
| Injection | Intravenous |
10
|
| Injection | Parenteral |
1000000 IU
|
| Injection | — |
|
| Injection | Intravenous |
5 IU
|
| Injection, solution | Intramuscular; Intravenous |
5 i.u./ml
|
| Injection, solution | Intramuscular; Intravenous |
|
| Injection, solution | Intramuscular; Intravenous |
10 [iU]/1mL
|
| Injection, solution | Parenteral |
5 U.I./ML
|
| Solution | Intramuscular; Intravenous |
2 IU/ml
|
| Solution | Parenteral |
|
| Solution | Parenteral |
5000000 IU
|
| Injection | Intramuscular; Intravenous |
10 IU
|
| Injection | Intramuscular; Intravenous |
10 iu/ml
|
| Solution | Intramuscular; Intravenous |
500000 IU
|
| Injection | Intramuscular; Intravenous |
|
| Injection | Intramuscular |
|
| Injection | — |
10 IU/ML
|
| Injection, solution | Intramuscular |
5 mg/5mg
|
| Injection | Intravenous |
10 IU/ml
|
| Solution | Parenteral |
5.000 UI
|
| Solution | Intravenous |
5.000 UI
|
| Solution | — |
10 IU/1ml
|
Target Information
| Role | Uniprot_ID | Gene_Name | Entity_Name | Organism | Actions | Internal link |
|---|---|---|---|---|---|---|
| target | P30559 | OXTR | Oxytocin receptor | Homo sapiens | agonist | Link |
| target | P47901 | AVPR1B | Vasopressin V1b receptor | Homo sapiens | agonist | Link |
| target | P30518 | AVPR2 | Vasopressin V2 receptor | Homo sapiens | agonist | Link |
| target | P37288 | AVPR1A | Vasopressin V1a receptor | Homo sapiens | agonist | Link |
| enzyme | P48147 | PREP | Prolyl endopeptidase | Homo sapiens | substrate | Link |
| enzyme | Q9UIQ6 | LNPEP | Leucyl-cystinyl aminopeptidase | Homo sapiens | substrate | Link |
| transporter | Q15109 | AGER | Advanced glycosylation end product-specific receptor | Homo sapiens | binder | Link |
| carrier | P01178 | OXT | Oxytocin-neurophysin 1 | Homo sapiens | binder | Link |