PPIDT00171

Drug Information
NameInotuzumab ozogamicin
SequenceNot Available
DrugBank_IDDB05889
Typebiotech
IndicationIn the US, inotuzumab ozogamicin is indicated for the treatment of relapsed or refractory CD22-positive B-cell precursor acute lymphoblastic leukemia (ALL) in adult and pediatric patients one year and older.[L50542] In Europe, it is indicated as monotherapy for the treatment of adults with relapsed or refractory CD22-positive B cell precursor ALL. Patients with Philadelphia chromosome positive (Ph+) relapsed or refractory B cell precursor ALL should have failed treatment with at least 1 tyrosine kinase inhibitor (TKI).[L938]

Dosage Forms
Form Route Strength
Injection, powder, for solution Intravenous
1 mg
Injection, powder, for solution Intravenous; Parenteral
1 MG
Injection, powder, lyophilized, for solution Intravenous
0.25 mg/1mL
Powder, for solution Intravenous
0.9 mg / vial
Injection, powder, for solution
1 mg
Powder, for solution Intravenous
1 mg
Target Information
Role Uniprot_ID Gene_Name Entity_Name Organism Actions Internal link
target P20273 CD22 B-cell receptor CD22 Homo sapiens antibody|regulator Link
transporter P08183 ABCB1 ATP-dependent translocase ABCB1 Homo sapiens substrate Link