PPIDT00176

Drug Information
NameLeronlimab
SequenceNot Available
DrugBank_IDDB05941
Typebiotech
IndicationLeronlimab is currently being investigated for the treatment of a number of cancers[A192858] and HIV.[A3922] Recently leronlimab has begun a phase II clinical trial in severely ill COVID-19 patients.[L12684] Preliminary data shows a reduction in the 'cytokine storm', particularly IL-6, as well as a normalization of the CD4/CD8 T-cell ratio.[L12684] These results may mitigate immune mediate injury seen in severely ill COVID-19 patients.[L12684]

Dosage Forms
Form Route Strength
No dosage records.
Target Information
Role Uniprot_ID Gene_Name Entity_Name Organism Actions Internal link
target P51681 CCR5 C-C chemokine receptor type 5 Homo sapiens antagonist Link