PPIDT00179

Drug Information
NameOlaratumab
SequenceQLQLQESGPGLVKPSETLSLTCTVSGGSINSSSYYWGWLRQSPGKGLEWIGSFFYTGSTYYNPSLRSRLTISVDTSKNQFSLMLSSVTAADTAVYYCARQSTYYYGSGNYYGWFDRWDQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
DrugBank_IDDB06043
Typebiotech
IndicationOlaratumab is indicated, in combination with doxorubicin, for the treatment of adult patients with advanced or mestastatic soft tissue sarcoma (STS) with a histologic subtype for which an anthracycline-containing regimen is appropriate and which is not amenable to curative treatment with radiotherapy or surgery.

Dosage Forms
Form Route Strength
Injection, solution Intravenous
10 mg/1mL
Injection, solution, concentrate Intravenous
10 mg/ml
Injection, solution, concentrate Intravenous; Parenteral
10 MG/ML
Solution Intravenous
190 mg / 19 mL
Solution Intravenous
500 mg / 50 mL
Target Information
Role Uniprot_ID Gene_Name Entity_Name Organism Actions Internal link
target P16234 PDGFRA Platelet-derived growth factor receptor alpha Homo sapiens antagonist Link