PPIDT00180
Drug Information
| Name | Trofinetide |
|---|---|
| Sequence | Not Available |
| DrugBank_ID | DB06045 |
| Type | small molecule |
| Indication | Trofinetide is indicated for the treatment of Rett syndrome in adults and pediatric patients two years of age and older.[L45628] |
Dosage Forms
| Form | Route | Strength |
|---|---|---|
| Solution | Oral |
200 mg / mL
|
| Solution | Oral |
200 mg/1mL
|
Target Information
| Role | Uniprot_ID | Gene_Name | Entity_Name | Organism | Actions | Internal link |
|---|---|---|---|---|---|---|
| enzyme | P08684 | CYP3A4 | Cytochrome P450 3A4 | Homo sapiens | inhibitor | Link |
| enzyme | O60656 | UGT1A9 | UDP-glucuronosyltransferase 1A9 | Homo sapiens | inhibitor | Link |
| enzyme | P16662 | UGT2B7 | UDP-glucuronosyltransferase 2B7 | Homo sapiens | inhibitor | Link |
| enzyme | P54855 | UGT2B15 | UDP-glucuronosyltransferase 2B15 | Homo sapiens | inhibitor | Link |
| transporter | Q9Y6L6 | SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Homo sapiens | inhibitor | Link |
| transporter | Q9NPD5 | SLCO1B3 | Solute carrier organic anion transporter family member 1B3 | Homo sapiens | inhibitor | Link |