PPIDT00203

Drug Information
NamePertuzumab
SequenceDIQMTQSPSSLSASVGDRVTITCKASQDVSIGVAWYQQKPGKAPKLLIYSASYRYTGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYYIYPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
DrugBank_IDDB06366
Typebiotech
IndicationPertuzumab is indicated for intravenous administration in combination with [trastuzumab] and [docetaxel] for the treatment of patients with HER2-positive metastatic breast cancer who have not received prior anti-HER2 therapy or chemotherapy for metastatic disease.[L14747] It is also indicated in combination with trastuzumab and other chemotherapies for the neoadjuvant treatment of HER2-positive locally advanced, inflammatory, or early-stage breast cancer as part of a complete treatment regimen[L14747] and as adjuvant treatment in patients with HER2-positive early-stage breast cancer at high risk of recurrence.[L14747] Pertuzumab is also indicated for subcutaneous injection - in combination with trastuzumab and [hyaluronidase] - in the treatment of HER2-positive breast cancers in adults.[L14510]

Dosage Forms
Form Route Strength
Injection Intravenous
30 MG/ML
Injection, solution, concentrate Intravenous
30 mg/1mL
Injection, solution, concentrate Intravenous
420 mg/14ml
Injection, solution, concentrate Intravenous
420 MG
Injection, solution, concentrate Intravenous; Parenteral
420 MG
Solution Intravenous
420 mg / 14 mL
Solution Intravenous
420.000 mg
Injection, solution, concentrate Parenteral
420 mcg/14mL
Injection, solution, concentrate Intravenous
Solution Intravenous
30 mg/ml
Kit; powder, for solution; solution Intravenous
Solution, concentrate Intravenous
42000000 mg
Injection, solution Subcutaneous
Solution Subcutaneous
Injection, solution Subcutaneous
1200 mg
Injection, solution Subcutaneous
600 mg
Solution Subcutaneous
6000000 mg
Solution Intravenous
420 mg/14ml
Target Information
Role Uniprot_ID Gene_Name Entity_Name Organism Actions Internal link
target P04626 ERBB2 Receptor tyrosine-protein kinase erbB-2 Homo sapiens binder|antibody Link