PPIDT00231
Drug Information
| Name | Aprotinin |
|---|---|
| Sequence | RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGGA |
| DrugBank_ID | DB06692 |
| Type | biotech |
| Indication | For prophylactic use to reduce perioperative blood loss and the need for blood transfusion in patients undergoing cardiopulmonary bypass in the course of coronary artery bypass graft surgery who are at an increased risk for blood loss and blood transfusion. |
Dosage Forms
| Form | Route | Strength |
|---|---|---|
| Solution | Topical |
|
| Solution | Topical |
360 -
|
| Solution | — |
|
| Powder, for solution | Topical |
|
| Kit | Topical |
|
| Powder | Topical |
|
| Kit; solution | — |
|
| Solution | Topical |
3000 KIU/ml
|
| Powder | Soft tissue |
|
| Solution | Intravenous |
10000 unit / mL
|
| Solution | Intravenous |
1000000 1/100mL
|
| Solution | Intravenous |
2000000 1/200mL
|
| Solution | Intravenous |
10000 KIE/ml
|
| Liquid | Intravenous |
100000 unit / amp
|
| Injection | Intravenous |
500000 kiu/50ml
|
Target Information
| Role | Uniprot_ID | Gene_Name | Entity_Name | Organism | Actions | Internal link |
|---|---|---|---|---|---|---|
| target | P07477 | PRSS1 | Serine protease 1 | Homo sapiens | unknown | Link |
| target | P17538 | CTRB1 | Chymotrypsinogen B | Homo sapiens | unknown | Link |
| target | P00747 | PLG | Plasminogen | Homo sapiens | unknown | Link |
| target | P06870 | KLK1 | Kallikrein-1 | Homo sapiens | unknown | Link |
| enzyme | P06276 | BCHE | Cholinesterase | Homo sapiens | inhibitor | Link |