PPIDT00245

Drug Information
NameLinaclotide
SequenceNot Available
DrugBank_IDDB08890
Typesmall molecule
IndicationLinaclotide is indicated for the treatment of irritable bowel syndrome with constipation in adults. This indication is approved in the US, Canada, and Europe.[L47211, L47216, L47221] In the US and Canada, it is also indicated for the treatment of chronic idiopathic constipation in adults.[L47211, L47221] In the US, it is also indicated for the treatment of functional constipation in pediatric patients 6 to 17 years of age.[L47211]

Dosage Forms
Form Route Strength
Capsule Oral
145 mcg
Capsule Oral
290 MICROGRAMMI
Capsule Oral
290 mcg
Capsule Oral
72 mcg
Capsule Oral
0.145 mg
Capsule, gelatin coated Oral
145 ug/1
Capsule, gelatin coated Oral
290 ug/1
Capsule, gelatin coated Oral
72 ug/1
Target Information
Role Uniprot_ID Gene_Name Entity_Name Organism Actions Internal link
target P25092 GUCY2C Guanylyl cyclase C Homo sapiens agonist Link