PPIDT00270
Drug Information
| Name | Turoctocog alfa |
|---|---|
| Sequence | ATRRYYLGAVELSWDYMQSDLGELPVDARFPPRVPKSFPFNTSVVYKKTLFVEFTDHLFNIAKPRPPWMGLLGPTIQAEVYDTVVITLKNMASHPVSLHAVGVSYWKASEGAEYDDQTSQREKEDDKVFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVKDLNSGLIGALLVCREGSLAKEKTQTLHKFILLFAVFDEGKSWHSETKNSLMQDRDAASARAWPKMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISPITFLTAQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPQLRMKNNEEAEDYDDDLTDSEMDVVRFDDDNSPSFIQIRSVAKKHPKTWVHYIAAEEEDWDYAPLVLAPDDRSYKSQYLNNGPQRIGRKYKKVRFMAYTDETFKTREAIQHESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVRPLYSRRLPKGVKHLKDFPILPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFVNMERDLASGLIGPLLICYKESVDQRGNQIMSDKRNVILFSVFDENRSWYLTENIQRFLPNPAGVQLEDPEFQASNIMHSINGYVFDSLQLSVCLHEVAYWYILSIGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWILGCHNSDFRNRGMTALLKVSSCDKNTGDYYEDSYEDISAYLLSKNNAIEPRSFSQNSRHPSQNPPVLKRHQR |
| DrugBank_ID | DB09109 |
| Type | biotech |
| Indication | Turoctocog alfa is indicated for the treatment and prophylaxis of bleedings in patients presenting hemophilia A.[L1105] The treatment with turoctocog alfa is related with its use to control bleeding episodes or as a perioperative management.[L1106] Hemophilia A is a hereditary hemorrhagic disorder generated by the congenital deficit of the coagulation factor VIII. This disease is manifested as excessive spontaneous or trauma-driven bleeding. The coagulation factor VIII is a robust initiator of thrombin which is later required for the generation of fibrin to form a platelet plug and its gene is expressed in the X chromosome.[A31505] |
Dosage Forms
| Form | Route | Strength |
|---|---|---|
| Solution | Intravenous |
500 UI
|
| Injection, powder, for solution | Intravenous |
1500 IU
|
| Injection, powder, for solution | Intravenous |
2000 IU
|
| Injection, powder, for solution | Intravenous |
3000 IU
|
| Solution | Intravenous |
250.00 UI
|
| Injection, powder, for solution | Parenteral |
1000 iu
|
| Injection, powder, for solution | Parenteral |
1500 iu
|
| Injection, powder, for solution | Parenteral |
2000 iu
|
| Injection, powder, for solution | Parenteral |
250 iu
|
| Injection, powder, for solution | Parenteral |
3000 iu
|
| Injection, powder, for solution | Parenteral |
500 iu
|
| Injection, powder, for solution | Intravenous |
|
| Injection, powder, for solution | Intravenous |
1000 IU
|
| Injection, powder, for solution | Intravenous |
250 IU
|
| Injection, powder, for solution | Intravenous |
500 IU
|
| Injection, powder, lyophilized, for solution | Intravenous |
150000000 IU
|
| Injection, powder, lyophilized, for solution | Intravenous |
200000000 IU
|
| Injection, powder, lyophilized, for solution | Intravenous |
25000000 IU
|
| Injection, powder, lyophilized, for solution | Intravenous |
300000000 IU
|
| Injection, powder, for solution | Intravenous |
100000000 IU
|
| Injection, powder, lyophilized, for solution | Intravenous |
50000000 IU
|
| Kit; powder, for solution | Intravenous |
1000 unit / vial
|
| Kit; powder, for solution | Intravenous |
1500 unit / vial
|
| Kit; powder, for solution | Intravenous |
2000 unit / vial
|
| Kit; powder, for solution | Intravenous |
250 unit / vial
|
| Kit; powder, for solution | Intravenous |
3000 unit / vial
|
| Kit; powder, for solution | Intravenous |
500 unit / vial
|
| Injection, powder, for solution | — |
250 IU
|
| Injection, powder, for solution | — |
500 IU
|