PPIDT00273
Drug Information
| Name | Sincalide |
|---|---|
| Sequence | Not Available |
| DrugBank_ID | DB09142 |
| Type | biotech |
| Indication | As the product Kinevac (FDA), sincalide is used for the following indications: 1) to stimulate gallbladder contraction, as may be assessed by various methods of diagnostic imaging, or to obtain by duodenal aspiration a sample of concentrated bile for analysis of cholesterol, bile salts, phospholipids, and crystals; (2) to stimulate pancreatic secretion in combination with secretin prior to obtaining a duodenal aspirate for analysis of enzyme activity, composition, and cytology; (3) to accelerate the transit of a barium meal through the small bowel, thereby decreasing the time and extent of radiation associated with fluoroscopy and x-ray examination of the intestinal tract.[L48541] |
Dosage Forms
| Form | Route | Strength |
|---|---|---|
| Injection, powder, lyophilized, for solution | Intravenous |
5 ug/5mL
|
| Powder, for solution | Intravenous |
5 mcg / vial
|
| Injection, powder, lyophilized, for solution | Intravenous |
3 ug/1
|
Target Information
| Role | Uniprot_ID | Gene_Name | Entity_Name | Organism | Actions | Internal link |
|---|---|---|---|---|---|---|
| target | P32238 | CCKAR | Cholecystokinin receptor type A | Homo sapiens | agonist | Link |
| target | P32239 | CCKBR | Gastrin/cholecystokinin type B receptor | Homo sapiens | agonist | Link |
| transporter | Q9NPD5 | SLCO1B3 | Solute carrier organic anion transporter family member 1B3 | Homo sapiens | substrate | Link |