PPIDT00274
Drug Information
| Name | Conestat alfa |
|---|---|
| Sequence | Not Available |
| DrugBank_ID | DB09228 |
| Type | biotech |
| Indication | For the treatment of acute attacks of hereditary angioedema (HAE) due to C1 esterase inhibitor deficiency in adults. |
Dosage Forms
| Form | Route | Strength |
|---|---|---|
| Injection, powder, for solution | Parenteral |
1500 IU
|
| Injection, powder, for solution | Parenteral |
2000 I.E.
|
| Injection, powder, for solution | Parenteral |
3000 I.E.
|
| Injection, powder, for solution | Parenteral |
500 I.E.
|
| Injection, powder, for solution | Intravenous |
2100 U
|
| Injection, powder, for solution | Intravenous |
2100 U/1
|
| Injection, solution | Intravenous |
|
Target Information
| Role | Uniprot_ID | Gene_Name | Entity_Name | Organism | Actions | Internal link |
|---|---|---|---|---|---|---|
| target | P00736 | C1R | Complement C1r subcomponent | Homo sapiens | inhibitor | Link |
| target | P09871 | C1S | Complement C1s subcomponent | Homo sapiens | inhibitor | Link |
| target | P03952 | KLKB1 | Plasma kallikrein | Homo sapiens | inhibitor | Link |
| target | P00748 | F12 | Coagulation factor XII | Homo sapiens | inhibitor | Link |
| target | P00734 | F2 | Prothrombin | Homo sapiens | inhibitor | Link |
| target | P03951 | F11 | Coagulation factor XI | Homo sapiens | inhibitor | Link |
| target | P00750 | PLAT | Tissue-type plasminogen activator | Homo sapiens | inhibitor | Link |