PPIDT00279

Drug Information
NameDaratumumab
SequenceEVQLLESGGGLVQPGGSLRLSCAVSGFTFNSFAMSWVRQAPGKGLEWVSAISGSGGGTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYFCAKDKILWFGEPVFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
DrugBank_IDDB09331
Typebiotech
IndicationDaratumumab is indicated as an intravenous injection alone or in combination with other medications for the treatment of multiple myeloma.[L13290] It is available as a combination product with [hyaluronidase] for the treatment of adults with multiple myeloma as monotherapy or combination therapy and light chain amyloidosis in combination with other drugs.[L13296]

Dosage Forms
Form Route Strength
Injection, solution Subcutaneous
1800 MG
Injection, solution, concentrate Intravenous
100 mg/5mL
Injection, solution, concentrate Intravenous
20 mg/1ml
Injection, solution, concentrate Intravenous
20 MG/ML
Injection, solution, concentrate Intravenous; Parenteral
20 MG/ML
Solution Intravenous
100 mg / 5 mL
Solution Intravenous
400 mg / 20 mL
Injection, solution, concentrate
100 mg/5ml
Solution, concentrate Intravenous
20 mg
Solution, concentrate Intravenous
2000000 mg
Injection, solution Intravenous
20 mg/mL
Injection, solution, concentrate
400 mg/20ml
Solution Intravenous
20 mg/mL
Injection Subcutaneous
Solution Subcutaneous
1800 mg / 15 mL
Injection, solution Subcutaneous
1800 mg/15mL
Solution Subcutaneous
120 mg
Solution Subcutaneous
12000000 mg
Target Information
Role Uniprot_ID Gene_Name Entity_Name Organism Actions Internal link
target P28907 CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Homo sapiens antibody Link