PPIDT00289

Drug Information
NameProtein C
SequenceNot Available
DrugBank_IDDB11312
Typebiotech
IndicationProtein C concentrate is indicated for pediatric and adult patients with severe congenital protein C deficiency for the prevention and treatment of venous thrombosis and purpura fulminans.[L12831] It is also found as a component of some prothrombin complex concentrate (i.e. [Factor IX Complex (Human)]) formulations, such as Kcentra.[L12834] Along with other blood coagulation factors, it is used to reverse acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with a need for an urgent surgery/invasive procedure.[L50517]

Dosage Forms
Form Route Strength
Powder, for solution Intravenous
Injection, powder, for solution Parenteral
Injection, powder, for solution Intravenous
Injection, powder, for solution Intravenous
1000 IU
Injection, powder, for solution Intravenous
500 IU
Injection, powder, for solution Intravenous; Subcutaneous
1000 IU
Injection, powder, for solution Intravenous; Subcutaneous
500 IU
Injection, powder, lyophilized, for solution; kit Intravenous
1000 [iU]/10mL
Injection, powder, lyophilized, for solution; kit Intravenous
500 [iU]/5mL
Kit Intravenous
100 [iU]/1mL
Injection, solution Intravenous
500 iu
Injection Intravenous
Injection, powder, lyophilized, for solution; kit Intravenous
Kit; powder, for solution Intravenous
Injection, powder, for solution Intravenous drip
520 IU/vial
Target Information
Role Uniprot_ID Gene_Name Entity_Name Organism Actions Internal link
target P12259 F5 Coagulation factor V Homo sapiens inactivator Link
target P00451 F8 Coagulation factor VIII Homo sapiens inactivator Link