PPIDT00363

Drug Information
NameBezlotoxumab
SequenceEVQLVQSGAEVKKSGESLKISCKGSGYSFTSYWIGWVRQMPGKGLEWMGIFYPGDSSTRYSPSFQGQVTISADKSVNTAYLQWSSLKASDTAMYYCARRRNWGNAFDIWGQGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
DrugBank_IDDB13140
Typebiotech
IndicationBezlotoxumab is indicated to reduce the recurrence of _Clostridioides difficile_ infection (CDI) in patients who are receiving antibacterial drug treatment for CDI and are at high risk for CDI recurrence.[L46976, L47191] In the US, the drug is approved for use in patients one year of age and older.[L46976] In Europe, it is approved in adults only.[L47191]

Dosage Forms
Form Route Strength
Injection, solution Intravenous
25 mg/1mL
Injection, solution, concentrate Intravenous
25 mg/ml
Injection, solution, concentrate Intravenous; Parenteral
25 MG/ML
Target Information
Role Uniprot_ID Gene_Name Entity_Name Organism Actions Internal link
target P18177 tcdB Toxin B Clostridioides difficile antibody|neutralizer Link