PPIDT00364

Drug Information
NameLenograstim
SequenceNot Available
DrugBank_IDDB13144
Typebiotech
IndicationThe drug is used to reduce the risk of life-threatening infection in patients with neutropenia, particularly after cytotoxic chemotherapy. Lenograstim is indicated as a treatment to reduce the duration of neutropenia and the severity of infections in patients with non-myeloid malignancy who have undergone autologous or allogeneic bone marrow transplantation, or treatment with established cytotoxic chemotherapy and in addition to reduce the incidence of infection associated with established cytotoxic chemotherapy. Lenograstim is also indicated to mobilise peripheral blood progenitor cells (PBPCs) with Lenograstim alone, or after myelosuppressive chemotherapy, in order to accelerate haematopoietic recovery by infusion of such cells, after myelosuppressive or myeloablative therapy. Lenograstim is also indicated to accelerate the engraftment of these cells after their reinfusion. GRANOCYTE is also indicated for the treatment of severe chronic neutropenia including congenital agranulocytosis (Kostmann's syndrome).

Dosage Forms
Form Route Strength
Injection, powder, for solution Intravenous; Subcutaneous
13000.000 IU/ml
Injection, powder, for solution Intravenous; Subcutaneous
263 mcg
Injection, powder, for solution Intravenous; Subcutaneous
33.6 MIU
Injection, powder, for solution Intravenous; Subcutaneous
263 mcg/ml
Injection, powder, for solution Intravenous; Subcutaneous
34 mIU/ml
Injection, powder, lyophilized, for solution Intravenous
263 ug
Injection, powder, for solution Intravenous; Subcutaneous
13 million IU/ml
Injection, powder, for solution Intravenous; Subcutaneous
34 million IU/ml
Powder
100 mcg/1vial
Powder
250 mcg/1vial
Target Information
Role Uniprot_ID Gene_Name Entity_Name Organism Actions Internal link
target Q99062 CSF3R Granulocyte colony-stimulating factor receptor Homo sapiens agonist Link