PPIDT00366

Drug Information
NameCoagulation factor VII human
SequenceNot Available
DrugBank_IDDB13150
Typebiotech
IndicationMay be administered in cases of uncontrolled bleeding. Factor VII alone can be used in the treatment of congenital hemophilia A or B, acquired hemophilia, congenital factor VII deficiency, and Glanzmann's thrombasthenia. Off label use in the treatment of refractory bleeding after cardiac surgery and warfarin related intracerebral hemorrhage. Brands for human factor VII are currently only in combination with other vitamin K coagulation factors and can be used to reverse vitamin K antagonist activity in patients with acute major bleeds or for urgent surgery/invasive procedures. Along with other blood coagulation factors, it is used to reverse acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with a need for an urgent surgery/invasive procedure.[L50517]

Dosage Forms
Form Route Strength
Injection, powder, for solution Intravenous
Injection Intravenous
Injection, powder, lyophilized, for solution Intravenous
60000000 IU
Injection, powder, for solution Parenteral
600 I.E.
Powder, for solution Intravenous
Injection, powder, lyophilized, for solution; kit Intravenous
Kit; powder, for solution Intravenous
Injection, powder, for solution Intravenous drip
520 IU/vial
Injection, powder, for solution Parenteral
Injection, powder, lyophilized, for solution Intravenous
200 IU/10ml
Injection, powder, lyophilized, for solution Intravenous
500 IU/10ml
Powder, for solution Intravenous
200 UI
Powder, for solution Intravenous
600 UI
Target Information
Role Uniprot_ID Gene_Name Entity_Name Organism Actions Internal link
target P13726 F3 Tissue factor Homo sapiens activator Link
target P00742 F10 Coagulation factor X Homo sapiens activator Link
target P00740 F9 Coagulation factor IX Homo sapiens activator Link