PPIDT00367
Drug Information
| Name | Anti-inhibitor coagulant complex |
|---|---|
| Sequence | Not Available |
| DrugBank_ID | DB13151 |
| Type | biotech |
| Indication | For use in the control of bleeding episodes, perioperative management, and routine prophylaxis against bleeding episodes in hemophilia A and B patients with inhibitors.[FDA Label] It is not indicated in the absence of factor VIII or IX inhibitors. |
Dosage Forms
| Form | Route | Strength |
|---|---|---|
| Kit; powder, for solution | Intravenous |
1000 U/20mL
|
| Kit; powder, for solution | Intravenous |
2500 U/50mL
|
| Kit; powder, for solution | Intravenous |
500 U/10mL
|
| Injection, powder, for solution | Parenteral |
100 E./ml
|
| Injection, powder, for solution | Intravenous |
50 u/ml
|
| Injection, powder, lyophilized, for solution | Intravenous |
1000 U
|
| Injection, powder, for solution | Parenteral |
25 E./ml
|
| Injection, powder, for solution | Parenteral |
50 E./ml
|
| Injection, powder, for solution | Intravenous |
25 u/ml
|
| Kit | Intravenous |
1000 [USP'U]/20mL
|
| Kit | Intravenous |
2500 [USP'U]/50mL
|
| Kit | Intravenous |
500 [USP'U]/20mL
|
| Kit; powder, for solution | Intravenous |
1300 unit / vial
|
| Kit; powder, for solution | Intravenous |
3250 unit / vial
|
| Kit; powder, for solution | Intravenous |
650 unit / vial
|
| Injection, powder, for solution | Intravenous |
1000 iu/1vial
|
| Injection, powder, for solution | Intravenous |
500 iu/1vial
|
Target Information
| Role | Uniprot_ID | Gene_Name | Entity_Name | Organism | Actions | Internal link |
|---|---|---|---|---|---|---|
| target | P00742 | F10 | Coagulation factor X | Homo sapiens | agonist | Link |
| target | P00734 | F2 | Prothrombin | Homo sapiens | agonist | Link |
| target | P02671 | FGA | Fibrinogen alpha chain | Homo sapiens | cleavage | Link |
| target | P02675 | FGB | Fibrinogen beta chain | Homo sapiens | cleavage | Link |
| target | P00488 | F13A1 | Coagulation factor XIII A chain | Homo sapiens | agonist | Link |
| target | P12259 | F5 | Coagulation factor V | Homo sapiens | agonist | Link |
| target | P00451 | F8 | Coagulation factor VIII | Homo sapiens | agonist | Link |
| target | P08709 | F7 | Coagulation factor VII | Homo sapiens | agonist | Link |