PPIDT00368
Drug Information
| Name | Coagulation Factor IX Human |
|---|---|
| Sequence | YNSGKLEEFVQGNLERECMEEKCSFEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGRCEQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSVSQTSKLTRAEAVFPDVDYVNSTEAETILDNITQSTQSFNDFTRVVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT |
| DrugBank_ID | DB13152 |
| Type | biotech |
| Indication | Factor IX is used to treat Christmas disease. Factor IX deficiency is treated by injection factor IX produced from human plasma. Along with other blood coagulation factors, it is used to reverse acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with a need for an urgent surgery/invasive procedure.[L50517] |
Dosage Forms
| Form | Route | Strength |
|---|---|---|
| Injection | Intravenous |
800 UI
|
| Injection, powder, for solution | Intravenous |
200 UI
|
| Injection, powder, for solution | Intravenous |
500 UI
|
| Injection, powder, for solution | Intravenous |
800 UI
|
| Powder, for solution | Intravenous |
1000 U.I.
|
| Powder, for solution | Intravenous |
200 U.I./5ML
|
| Powder, for solution | Intravenous |
500 U.I.
|
| Injection, solution | Intravenous |
500 IU/10mL
|
| Injection, powder, for solution | Intravenous |
10000000 IU
|
| Injection, powder, for solution | Intravenous |
1500 IU/10ML
|
| Injection, solution | Intravenous |
1000 U.I.
|
| Injection, solution | Intravenous |
500 U.I.
|
| Powder, for solution | Parenteral |
1000 U.I.
|
| Powder, for solution | Parenteral |
1500 U.I.
|
| Powder, for solution | Parenteral |
500 U.I.
|
| Injection, powder, lyophilized, for solution | Intravenous |
5000000 IU
|
| Kit | Intravenous |
|
| Injection, powder, for solution | Intravenous |
1000 IU/10ml vial
|
| Injection, powder, for solution | Intravenous |
1500 IU/10ml vial
|
| Injection, powder, for solution | Intravenous |
500 IU/10ml vial
|
| Kit | Intravenous |
30 [iU]/1mL
|
| Kit | Intravenous |
300 [iU]/1mL
|
| Injection, powder, for solution | Intravenous; Parenteral |
1500 IU
|
| Injection, powder, for solution | Intravenous; Parenteral |
250 IU
|
| Injection, powder, for solution | Parenteral |
1000 IU
|
| Injection, powder, for solution | Parenteral |
2000 IU
|
| Injection, powder, for solution | Parenteral |
500 IU
|
| Solution | Parenteral |
600.00 UI
|
| Powder, for solution | Intravenous |
|
| Solution | Parenteral |
250 UI
|
| Injection, powder, for solution | Parenteral |
|
| Injection, powder, lyophilized, for solution | Intravenous |
500 iu/10ml
|
| Injection | Intravenous |
|
| Injection, powder, for solution | Intravenous |
1200 IU
|
| Injection, powder, for solution | Parenteral |
200 U.I.
|
| Injection, powder, for solution | Parenteral |
600 U.I.
|
| Injection, powder, for solution | Parenteral |
100 IU/ml
|
| Injection, powder, for solution | Parenteral |
50 IU/ml
|
| Injection, powder, for solution | Parenteral |
100 I.E./ml
|
| Injection, solution | Intravenous |
1000 iu/10ml
|
| Injection, solution | Intravenous |
500 iu/5ml
|
| Injection, powder, for solution | Intravenous; Parenteral |
3500 UI
|
| Injection, powder, for solution | Parenteral |
1200 I.E.
|
| Injection, powder, for solution | Intravenous |
120 IU/mL
|
| Injection, powder, for solution | Parenteral |
200 I.E.
|
| Injection, powder, for solution | Parenteral |
600 I.E.
|
| Powder, for solution | — |
|
| Powder, for solution | Intravenous |
720 unit / 5 mL
|
| Injection, powder, for solution | Intravenous |
1000 IU/10ML
|
| Powder, for solution | Parenteral |
200 UI/5ML
|
| Powder, for solution | Parenteral |
500 UI/10ML
|
| Injection, powder, lyophilized, for solution; kit | Intravenous |
|
| Powder, for solution | Parenteral |
|
| Solution | Intravenous |
1000.00 UI
|
| Injection, powder, for suspension | Parenteral |
100000000 IU
|
| Injection, powder, for solution | Intravenous |
1000 IU
|
| Injection, powder, for solution | Intravenous |
250 IU
|
| Injection, powder, for solution | Intravenous |
500 IU
|
| Injection, powder, lyophilized, for solution | Intravenous |
100 [iU]/1mL
|
| Kit | Intravenous |
1000 [iU]/10mL
|
| Kit | Intravenous |
500 [iU]/5mL
|
| Solution | Parenteral |
1000.0 UI
|
| Injection, powder, for solution | Parenteral |
50 I.E./ml
|
| Injection, powder, lyophilized, for solution | Intravenous |
|
| Kit; powder, for solution | Intravenous |
|
| Injection, powder, for solution | Intravenous drip |
520 IU/vial
|
| Injection | Intravenous |
1000 IU/10ml
|
| Injection | Intravenous |
1500 IU/10ml
|
| Injection | Intravenous |
500 IU/5ml
|
| Injection, powder, for solution | Parenteral |
|
| Injection, powder, for solution | Intravenous |
|
| Injection, powder, for solution | Intravenous |
1000 UI
|
| Injection, powder, for solution | Intravenous |
2000 UI
|
| Injection, powder, for solution | Intravenous |
3000 UI
|
| Solution | Parenteral |
500.000 UI
|
| Injection, powder, for solution | Intravenous |
|
| Injection, powder, for solution | — |
50 iu/1vial
|
| Injection, powder, for solution | Intravenous |
500 iu/vial
|
| Injection, powder, lyophilized, for solution | Intravenous |
25000000 IU
|
| Solution | Intravenous |
|
| Injection, powder, for solution | — |
600 iu/1vial
|
| Powder | — |
100 iu/1vial
|
Target Information
| Role | Uniprot_ID | Gene_Name | Entity_Name | Organism | Actions | Internal link |
|---|---|---|---|---|---|---|
| target | P00742 | F10 | Coagulation factor X | Homo sapiens | activator | Link |
| target | P03951 | F11 | Coagulation factor XI | Homo sapiens | ligand | Link |
| target | P08709 | F7 | Coagulation factor VII | Homo sapiens | ligand | Link |
| target | P00451 | F8 | Coagulation factor VIII | Homo sapiens | cofactor | Link |
| target | P00734 | F2 | Prothrombin | Homo sapiens | unknown | Link |
| target | Q07954 | LRP1 | Prolow-density lipoprotein receptor-related protein 1 | Homo sapiens | unknown | Link |
| target | P38435 | GGCX | Vitamin K-dependent gamma-carboxylase | Homo sapiens | unknown | Link |