PPIDT00371
Drug Information
| Name | Antihemophilic factor human |
|---|---|
| Sequence | MQIELSTCFFLCLLRFCFSATRRYYLGAVELSWDYMQSDLGELPVDARFPPRVPKSFPFNTSVVYKKTLFVEFTVHLFNIAKPRPPWMGLLGPTIQAEVYDTVVITLKNMASHPVSLHAVGVSYWKASEGAEYDDQTSQREKEDDKVFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVKDLNSGLIGALLVCREGSLAKEKTQTLHKFILLFAVFDEGKSWHSETKNSLMQDRDAASARAWPKMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISPITFLTAQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPQLRMKNNEEAEDYDDDLTDSEMDVVRFDDDNSPSFIQIRSVAKKHPKTWVHYIAAEEEDWDYAPLVLAPDDRSYKSQYLNNGPQRIGRKYKKVRFMAYTDETFKTREAIQHESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVRPLYSRRLPKGVKHLKDFPILPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFVNMERDLASGLIGPLLICYKESVDQRGNQIMSDKRNVILFSVFDENRSWYLTENIQRFLPNPAGVQLEDPEFQASNIMHSINGYVFDSLQLSVCLHEVAYWYILSIGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWILGCHNSDFRNRGMTALLKVSSCDKNTGDYYEDSYEDISAYLLSKNNAIEPRSFSQNSRHPSTRQKQFNATTIPENDIEKTDPWFAHRTPMPKIQNVSSSDLLMLLRQSPTPHGLSLSDLQEAKYETFSDDPSPGAIDSNNSLSEMTHFRPQLHHSGDMVFTPESGLQLRLNEKLGTTAATELKKLDFKVSSTSNNLISTIPSDNLAAGTDNTSSLGPPSMPVHYDSQLDTTLFGKKSSPLTESGGPLSLSEENNDSKLLESGLMNSQESSWGKNVSSTESGRLFKGKRAHGPALLTKDNALFKVSISLLKTNKTSNNSATNRKTHIDGPSLLIENSPSVWQNILESDTEFKKVTPLIHDRMLMDKNATALRLNHMSNKTTSSKNMEMVQQKKEGPIPPDAQNPDMSFFKMLFLPESARWIQRTHGKNSLNSGQGPSPKQLVSLGPEKSVEGQNFLSEKNKVVVGKGEFTKDVGLKEMVFPSSRNLFLTNLDNLHENNTHNQEKKIQEEIEKKETLIQENVVLPQIHTVTGTKNFMKNLFLLSTRQNVEGSYEGAYAPVLQDFRSLNDSTNRTKKHTAHFSKKGEEENLEGLGNQTKQIVEKYACTTRISPNTSQQNFVTQRSKRALKQFRLPLEETELEKRIIVDDTDTQWSKNMKHLTPSTLTQIDYNEKEKGAITQSPLSDCLTRSHSIPQANRSPLPIAKVSSFPSIRPIYLTRVLFQDNSSHLPAASYRKKDSGVQESSHFLQGAKKNNLSLAILTLEMTGDQREVGSLGTSATNSVTYKKVENTVLPKPDLPKTSGKVELLPKVHIYQKDLFPTETSNGSPGHLDLVEGSLLQGTEGAIKWNEANRPGKVPFLRVATESSAKTPSKLLDPLAWDNHYGTQIPKEEWKSQEKSPEKTAFKKKDTILSLNACESNHAIAAINEGQNKPEIEVTWAKQGRTERLCSQNPPVLKRHQREITRTTLQSDQEEIDYDDTISVEMKKEDFDIYDEDENQSPRSFQKKTRHYFIAAVERLWDYGMSSSPHVLRNRAQSGSVPQFKKVVFQEFTDGSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQASRPYSFYSSLISYEEDQRQGAEPRKNFVKPNETKTYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDVHSGLIGPLLVCHTNTLNPAHGRQVTVQEFALFFTIFDETKSWYFTENMERNCRAPCNIQMEDPTFKENYRFHAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENIHSIHFSGHVFTVRKKEEYKMALYNLYPGVFETVEMLPSKAGIWRVECLIGEHLHAGMSTLFLVYSNKCQTPLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWSTKEPFSWIKVDLLAPMIIHGIKTQGARQKFSSLYISQFIIMYSLDGKKWQTYRGNSTGTLMVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQDLY |
| DrugBank_ID | DB13192 |
| Type | biotech |
| Indication | The human antihemophilic factor is indicated for the cases of hemophilia A, also known as classical hemophilia for the prevention and control of hemorrhagic episodes.[L1055] If surgery is needed in patients with hemophilia A there is a need of correction of the clotting abnormality. In this cases, the human antihemophilic factor may be administered followed by intermittent maintenance doses.[L1053] The hemophilia A is characterized by the deficiency of the coagulation factor VIII that results in prolonged blood flow after injury or surgery as well as recurrent bleeding.[T56] |
Dosage Forms
| Form | Route | Strength |
|---|---|---|
| Injection, powder, for solution | Intravenous; Parenteral |
1000 IU
|
| Injection, powder, for solution | Intravenous; Parenteral |
2000 IU
|
| Injection, powder, for solution | Intravenous; Parenteral |
250 IU
|
| Injection, powder, for solution | Intravenous; Parenteral |
500 IU
|
| Injection, powder, for solution | — |
100 IU/ml
|
| Injection, powder, for solution | Parenteral |
100 I.E./ml
|
| Injection | Intravenous |
1000 iu
|
| Powder | Intravenous |
1000 IU
|
| Injection, powder, lyophilized, for solution | Intravenous |
100000000 IU
|
| Injection, powder, for solution | Parenteral |
200 I.E./ml
|
| Powder | Intravenous |
250 IU
|
| Injection | Intravenous |
500 iu
|
| Powder | Intravenous |
500 IU
|
| Injection, powder, lyophilized, for solution | Intravenous |
250 IU
|
| Solution | — |
|
| Injection, powder, for solution | Intravenous |
50 iu/mL
|
| Injection, powder, for solution | — |
1000 iu/10ml
|
| Injection | Intravenous |
1000 iu/10ml
|
| Injection, powder, for solution | — |
500 iu/10ml
|
| Injection | Intravenous |
500 iu/10ml
|
| Injection, powder, lyophilized, for solution | Intravenous |
50000000 IU
|
| Injection, powder, lyophilized, for solution | Intravenous |
1000 iu/10ml
|
| Injection, powder, lyophilized, for solution | Intravenous |
500 iu/5ml
|
| Powder, for solution | Intravenous |
15 unit / mL
|
| Injection, powder, lyophilized, for solution | Intravenous |
1500 iu/15ml
|
| Injection, powder, lyophilized, for solution | Intravenous |
250 iu/10ml
|
| Injection, powder, for solution | Intravenous |
250 IU/10mL
|
| Injection, powder, lyophilized, for solution | Intravenous |
500 iu/10ml
|
| Injection, powder, for solution | Intravenous |
1000 iu/vial
|
| Injection, powder, for solution | Intravenous |
250 iu
|
| Injection, powder, for solution | Intravenous |
500 iu
|
| Injection | Intravenous |
|
| Injection, powder, for solution | Parenteral |
|
| Injection, powder, lyophilized, for solution | Intravenous |
1000 iu
|
| Injection, powder, lyophilized, for solution | Parenteral |
25000000 IU
|
| Injection, powder, for solution | Parenteral |
50 I.E./ml
|
| Injection, powder, lyophilized, for solution | Intravenous |
50000000 mg
|
| Injection, powder, lyophilized, for solution | Intravenous |
500 iu
|
| Kit | Intravenous |
100 [iU]/1mL
|
| Kit | Intravenous |
170 [iU]/1mL
|
| Kit | Intravenous |
25 [iU]/1mL
|
| Kit | Intravenous |
50 [iU]/1mL
|
| Kit; powder, for solution | Intravenous |
1000 [iU]/10mL
|
| Kit; powder, for solution | Intravenous |
1700 [iU]/10mL
|
| Kit; powder, for solution | Intravenous |
250 [iU]/10mL
|
| Kit; powder, for solution | Intravenous |
500 [iU]/10mL
|
| Powder, for solution | Intravenous |
1700 unit / vial
|
| Injection, powder, for solution | Intravenous |
|
| Injection, powder, lyophilized, for solution | Intravenous |
25000000 IU
|
| Powder, for solution | Intravenous |
700 unit / vial
|
| Injection, powder, lyophilized, for solution | Intravenous |
|
| Injection, solution | Intravenous |
1200 iu/10ml
|
| Injection, solution | Intravenous |
600 iu/5ml
|
| Injection, powder, lyophilized, for solution; kit | Intravenous |
1000 [iU]/10mL
|
| Injection, powder, lyophilized, for solution; kit | Intravenous |
250 [iU]/5mL
|
| Injection, powder, lyophilized, for solution; kit | Intravenous |
500 [iU]/5mL
|
| Kit | Intravenous |
1000 [iU]/10mL
|
| Kit | Intravenous |
250 [iU]/5mL
|
| Kit | Intravenous |
500 [iU]/5mL
|
| Solution | Parenteral |
250 UI
|
| Injection, solution, concentrate | Intravenous |
250 IU/5mL
|
| Injection, powder, for solution | — |
250 IU
|
| Injection, powder, for solution | — |
500 IU
|
| Injection, powder, for solution | Intravenous |
1000 iu/10ml
|
| Injection, powder, for solution | Intravenous |
250 iu/5ml
|
| Injection, powder, for solution | Intravenous |
500 iu/5ml
|
| Liquid | Intravenous |
1800 unit / vial
|
| Powder, for solution | Intravenous |
1000 unit / vial
|
| Powder, for solution | Intravenous |
500 unit / vial
|
| Injection, powder, lyophilized, for solution; kit | Intravenous |
1500 [iU]/10mL
|
| Injection, powder, lyophilized, for solution; kit | Intravenous |
250 [iU]/2.5mL
|
| Kit | Intravenous |
|
| Kit; solution | Intravenous |
|
| Injection, powder, for solution | Intravenous |
1000 IU
|
| Injection, powder, for solution | Intravenous |
2000 IU
|
| Powder | Intravenous |
100 IU/mL
|
| Powder | Intravenous |
50 IU/mL
|
| Injection, powder, for solution | Intravenous |
500 iu/10ml
|
| Injection, powder, for solution | — |
|
| Liquid | Intravenous |
1000 unit / vial
|
| Solution | Intravenous |
|
| Injection, powder, for solution | Intravenous |
250 iu/vial
|
| Injection, powder, for solution | Intravenous |
500 iu/vial
|
| — | Intravenous |
|
| Powder | Intravenous |
|
| Injection, powder, lyophilized, for solution | Parenteral |
|
| Powder, for solution | Intravenous |
|
| Injection, powder, for solution | Parenteral |
|
| Injection, powder, for solution | Intravenous |
|