PPIDT00374

Drug Information
NameTisagenlecleucel
SequenceNot Available
DrugBank_IDDB13881
Typebiotech
IndicationTisagenlecleucel is indicated for use in individuals aged 25 years and younger with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.[L41230] It is also used to treat adult patients with relapsed or refractory (r/r) large B-cell lymphoma after two or more lines of systemic therapy including diffuse large B-cell lymphoma (DLBCL) not otherwise specified, high-grade B-cell lymphoma, and DLBCL arising from follicular lymphoma.[L41230] Tisagenlecleucel is also indicated in adult patients with relapsed or refractory follicular lymphoma after two or more lines of systemic therapy.[L41230]

Dosage Forms
Form Route Strength
Intravenous
300600000 cells
Injection, suspension Intravenous
2000001
Injection, suspension Intravenous
300600.000 cells
Injection, suspension Intravenous
60000001
Suspension Intravenous
600000000 cells
Target Information
Role Uniprot_ID Gene_Name Entity_Name Organism Actions Internal link
target P15391 CD19 B-lymphocyte antigen CD19 Homo sapiens antibody Link