PPIDT00381
Drug Information
| Name | Moroctocog alfa |
|---|---|
| Sequence | Not Available |
| DrugBank_ID | DB13999 |
| Type | biotech |
| Indication | Moroctocog alfa is indicated for use in adults and children with hemophilia A (congenital factor VIII deficiency) for on-demand treatment and control of bleeding episodes, perioperative management, and routine prophylaxis to reduce the frequency of bleeding episodes.[L41160, L41165, L41170] |
Dosage Forms
| Form | Route | Strength |
|---|---|---|
| Powder, for solution | Intravenous |
1000 unit / vial
|
| Injection, powder, for solution | Intravenous |
3000 IU
|
| Injection, solution | Intravenous |
1000 iu
|
| Injection, solution | Intravenous |
2000 iu
|
| Injection, solution | Intravenous |
250 iu
|
| Injection, solution | Intravenous |
500 iu
|
| Injection, powder, lyophilized, for solution; kit | Intravenous; Topical |
|
| Kit; powder, for solution | Intravenous |
1000 unit / vial
|
| Kit; powder, for solution | Intravenous |
2000 unit / vial
|
| Kit; powder, for solution | Intravenous |
250 unit / vial
|
| Kit; powder, for solution | Intravenous |
500 unit / vial
|
| Injection, powder, lyophilized, for solution | Intravenous |
100000000 IU
|
| Injection, powder, lyophilized, for solution | Intravenous |
500 IU
|
| Injection, powder, lyophilized, for solution | Intravenous |
50000000 IU
|
| Injection, powder, for solution | Intravenous |
|
| Injection, powder, for solution | Intravenous |
1000 IU
|
| Injection, powder, for solution | Intravenous |
2000 IU
|
| Injection, powder, for solution | Intravenous |
250 IU
|
| Injection, powder, for solution | Intravenous |
500 IU
|
| Powder, for solution | Intravenous |
1000 unit / syr
|
| Powder, for solution | Intravenous |
2000 unit / syr
|
| Powder, for solution | Intravenous |
250 unit / syr
|
| Powder, for solution | Intravenous |
3000 unit / syr
|
| Powder, for solution | Intravenous |
500 unit / syr
|
| Injection, powder, lyophilized, for solution | Intravenous |
200000000 IU
|
| Injection, powder, lyophilized, for solution | Intravenous |
250 IU
|
| Injection, powder, lyophilized, for solution | Intravenous |
25000000 IU
|
Target Information
| Role | Uniprot_ID | Gene_Name | Entity_Name | Organism | Actions | Internal link |
|---|---|---|---|---|---|---|
| target | P00742 | F10 | Coagulation factor X | Homo sapiens | activator | Link |
| target | P00740 | F9 | Coagulation factor IX | Homo sapiens | cofactor | Link |
| target | P04275 | VWF | von Willebrand factor | Homo sapiens | binder | Link |
| target | O14832 | PHYH | Phytanoyl-CoA dioxygenase, peroxisomal | Homo sapiens | antagonist | Link |
| target | P07307 | ASGR2 | Asialoglycoprotein receptor 2 | Homo sapiens | binder | Link |
| target | P11021 | HSPA5 | Endoplasmic reticulum chaperone BiP | Homo sapiens | chaperone | Link |
| target | P27797 | CALR | Calreticulin | Homo sapiens | chaperone | Link |
| target | P27824 | CANX | Calnexin | Homo sapiens | chaperone | Link |
| target | P49257 | LMAN1 | Protein ERGIC-53 | Homo sapiens | chaperone | Link |
| target | Q07954 | LRP1 | Prolow-density lipoprotein receptor-related protein 1 | Homo sapiens | modulator | Link |
| target | Q8NI22 | MCFD2 | Multiple coagulation factor deficiency protein 2 | Homo sapiens | modulator | Link |
| enzyme | P00734 | F2 | Prothrombin | Homo sapiens | activator | Link |
| enzyme | P04070 | PROC | Vitamin K-dependent protein C | Homo sapiens | inactivator | Link |