PPIDT00390

Drug Information
NameAndexanet alfa
SequenceANSFLFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRRKRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDAGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK
DrugBank_IDDB14562
Typebiotech
IndicationAndexanet alfa is indicated for patients treated with [rivaroxaban] and [apixaban], when reversal of anticoagulation is needed due to life-threatening or uncontrolled bleeding [L3725]. Andexxa has not been shown to be effective for, and is not indicated for, the treatment of bleeding related to any Factor Xa inhibitors other than apixaban and rivaroxaban [L3725].

Dosage Forms
Form Route Strength
Injection, powder, lyophilized, for solution Intravenous
100 mg/10mL
Injection, powder, lyophilized, for solution Intravenous
200 mg/20mL
Injection, powder, for solution Intravenous
200 mg
Powder, for solution Intravenous
200 mg / vial
Powder, for solution Intravenous
200 MG
Solution Intravenous
207.00 mg
Target Information
Role Uniprot_ID Gene_Name Entity_Name Organism Actions Internal link
target P10646 TFPI Tissue factor pathway inhibitor Homo sapiens inhibitor Link