PPIDT00403

Drug Information
NameRelatlimab
SequenceQVQLQQWGAGLLKPSETLSLTCAVYGGSFSDYYWNWIRQPPGKGLEWIGEINHRGSTNSNPSLKSRVTLSLDTSKNQFSLKLRSVTAADTAVYYCAFGYSDYEYNWFDPWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLG
DrugBank_IDDB14851
Typebiotech
IndicationRelatlimab is indicated in combination with [nivolumab], in the combination product Opdualag, for the treatment of adult and pediatric patients ≥12 years old with unresectable or metastatic melanoma.[L41265] In Canada and the EU, it is specifically indicated as a first-line treatment,[L50001,L50011] and the EU adds an additional requirement that tumor cell PD-L1 expression be < 1%.[L50011]

Dosage Forms
Form Route Strength
Injection Intravenous
Injection, solution, concentrate Intravenous
Solution Intravenous
Target Information
Role Uniprot_ID Gene_Name Entity_Name Organism Actions Internal link
target P18627 LAG3 Lymphocyte activation gene 3 protein Homo sapiens antibody Link