PPIDT00408

Drug Information
NameTislelizumab
SequenceQVQLQESGPGLVKPSETLSLTCTVSGFSLTSYGVHWIRQPPGKGLEWIGVIYADGSTNYNPSLKSRVTISKDTSKNQVSLKLSSVTAADTAVYYCARAYGNYWYIDVWGQGTTVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPPVAGGPSVFLFPPKPKDTLMISRTPEVTCVVVAVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVVHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGK
DrugBank_IDDB14922
Typebiotech
IndicationTislelizumab is indicated as monotherapy for the treatment of unresectable,[L49349, L50341] locally advanced,[L49349] or metastatic esophageal squamous cell carcinoma [L49349, L50341] in adults after prior systemic chemotherapy that did not include a PD-(L)1 inhibitor, such as platinum-based chemotherapy.[L49349, L50341]

Dosage Forms
Form Route Strength
Injection, solution, concentrate Intravenous
10 mg/ml
Injection, solution, concentrate Intravenous
10 mg/1mL
Injection, solution, concentrate Intravenous
100 mg
Target Information
Role Uniprot_ID Gene_Name Entity_Name Organism Actions Internal link
target Q15116 PDCD1 Programmed cell death protein 1 Homo sapiens inhibitor|antibody Link