PPIDT00444

Drug Information
NameBrexucabtagene autoleucel
SequenceNot Available
DrugBank_IDDB15699
Typebiotech
IndicationBrexucabtagene autoleucel is a modified autologous chimeric antigen receptor (CAR) T cell immunotherapy indicated for the treatment of relapsed or refractory mantle cell lymphoma (MCL) in adult patients.[L15148] It is additionally indicated for the treatment of adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).[L15148] Brexucabtagene autoleucel has been granted accelerated approval based on results from a single-arm, open-label, multicentre clinical trial; continued approval may be contingent on confirmatory trials.[L15148]

Dosage Forms
Form Route Strength
Suspension Intravenous
1000000 1/68mL
Suspension Intravenous
100000000 cells / bag
Suspension Intravenous
120000000 cells
Suspension Intravenous
2000000 1/68mL
Suspension Intravenous
200000000 cells / bag
Target Information
Role Uniprot_ID Gene_Name Entity_Name Organism Actions Internal link
target P15391 CD19 B-lymphocyte antigen CD19 Homo sapiens binder Link