PPIRE02030

Target Protein Information
Protein_Name SaV-like
Protein_Sequence MEDMVDHPPHYNQAGVECIDAIEAALGAENFEFYLQGNVMKYLWRYRYKNGVEDLQKAKWYLEKLIDSTYSP
Organism_Source uncultured virus
Functional_Classification other
Cellular_Localization Extracellular
Gene_Names None
UniProt_ID A0A0A0UXU9
Protein-Protein Interaction Networks
Peptide Basic Information
Peptide_Name SBP-Tag2
Peptide_Sequence HVVEGLAGELEQLRARLEHHPQG
Peptide_Length 23
Peptide_SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1c[nH]cn1)C(C)C)C(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)O
Chemical_Modification None
Cyclization_Method None
Linear/Cyclic Linear
N-terminal_Modification Free
C-terminal_Modification Free
Amino_Acid_Distribution
Peptide Physicochemical
Molecular_Weight 2575.87
Aliphatic_Index 101.73913
Aromaticity 0.00000
Average_Rotatable_Bonds 3.73913
Charge_at_pH_7 -1.72219
Isoelectric_Point 6.21745
Number_of_Hydrogen_Bond_Acceptors 35
Number_of_Hydrogen_Bond_Donors 38
Topological_Polar_Surface_Area 1139.95000
X_logP_energy -10.58536
Interaction Information
Affinity KD=1.53 nM
Affinity_Assay Surface plasmon resonance
PDB_ID 4JO6
Type Affinity ligand
Structure
Reference Information
Document_Type Research Articles
Title The structure of the SBP-Tag-streptavidin complex reveals a novel helical scaffold bridging binding pockets on separate subunits.
Release_Year 2013
PMID 23633599
DOI 10.1107/S0907444913002576