PPIRE02139

Target Protein Information
Protein_Name None
Protein_Sequence MAKKEMVEFDEAIHGEDLAKFIKEASDHKLKISGYNELIKDIRIRAKDELGVDGKMFNRLLALYHKDNRDVFEAETEEVVELYDTVFSK
Organism_Source Escherichia virus CAM-21
Functional_Classification Enzyme
Cellular_Localization Extracellular
Gene_Names dsbA
UniProt_ID A0A9E8YSS7
Protein-Protein Interaction Networks
Peptide Basic Information
Peptide_Name DsbB P2 peptide
Peptide_Sequence PSCGPGL
Peptide_Length 7
Peptide_SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CS)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)C(=O)O
Chemical_Modification None
Cyclization_Method None
Linear/Cyclic Linear
N-terminal_Modification Free
C-terminal_Modification Free
Amino_Acid_Distribution
Peptide Physicochemical
Molecular_Weight 629.73
Aliphatic_Index 55.71429
Aromaticity 0.00000
Average_Rotatable_Bonds 2.28571
Charge_at_pH_7 -0.06399
Isoelectric_Point 5.92254
Number_of_Hydrogen_Bond_Acceptors 10
Number_of_Hydrogen_Bond_Donors 9
Topological_Polar_Surface_Area 235.37000
X_logP_energy -3.53100
Interaction Information
Affinity KD=7.9 uM
Affinity_Assay Isothermal titration calorimetry
PDB_ID 4P3Y
Type Affinity ligand
Structure
Reference Information
Document_Type Research Articles
Title Structure of the Acinetobacter baumannii dithiol oxidase DsbA bound to elongation factor EF-Tu reveals a novel protein interaction site.
Release_Year 2014
PMID 24860094
DOI 10.1074/jbc.M114.571737