PPIRE02171

Target Protein Information
Protein_Name AraC family transcriptional regulator
Protein_Sequence MQTKILLSTGEVFLLPEIVYASALNALKHHTCFWFESKGEKYAFNPAHIVYIGLVNG
Organism_Source Arthronema virus TR020
Functional_Classification Transcriptional regulator
Cellular_Localization Cytoplasm
Gene_Names None
UniProt_ID A0A7G3WH12
Protein-Protein Interaction Networks
Peptide Basic Information
Peptide_Name Candidate1
Peptide_Sequence MFASNLVFSHMHMIMNKQQCSQMEKRGWVLSASHAASHGRIAEWEKVYSGVSMH
Peptide_Length 54
Peptide_SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCSC)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O)C(C)C)C(C)C
Chemical_Modification None
Cyclization_Method None
Linear/Cyclic Linear
N-terminal_Modification Free
C-terminal_Modification Free
Amino_Acid_Distribution
Peptide Physicochemical
Molecular_Weight 6193.16
Aliphatic_Index 59.62963
Aromaticity 0.09259
Average_Rotatable_Bonds 3.85185
Charge_at_pH_7 2.39414
Isoelectric_Point 9.37446
Number_of_Hydrogen_Bond_Acceptors 89
Number_of_Hydrogen_Bond_Donors 89
Topological_Polar_Surface_Area 2491.88000
X_logP_energy -24.95246
Interaction Information
Affinity KD=1.8 uM
Affinity_Assay Affinity chromatography
PDB_ID None
Type Affinity ligand
Structure
Reference Information
Document_Type Research Articles
Title Identification of oligomerizing peptides.
Release_Year 2001
PMID 11274194
DOI 10.1074/jbc.M102220200