PPIRE03060

Target Protein Information
Protein_Name SaV-like
Protein_Sequence MEDMVDHPPHYNQAGVECIDAIEAALGAENFEFYLQGNVMKYLWRYRYKNGVEDLQKAKWYLEKLIDSTYSP
Organism_Source uncultured virus
Functional_Classification other
Cellular_Localization Extracellular
Gene_Names None
UniProt_ID A0A0A0UXU9
Protein-Protein Interaction Networks
Peptide Basic Information
Peptide_Name wt
Peptide_Sequence DVEAWLDERVPLVET
Peptide_Length 15
Peptide_SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)O)[C@@H](C)O)C(C)C)C(C)C
Chemical_Modification None
Cyclization_Method None
Linear/Cyclic Linear
N-terminal_Modification Free
C-terminal_Modification Free
Amino_Acid_Distribution
Peptide Physicochemical
Molecular_Weight 1770.96
Aliphatic_Index 116.66667
Aromaticity 0.06667
Average_Rotatable_Bonds 3.66667
Charge_at_pH_7 -3.99580
Isoelectric_Point 3.63840
Number_of_Hydrogen_Bond_Acceptors 23
Number_of_Hydrogen_Bond_Donors 25
Topological_Polar_Surface_Area 746.35000
X_logP_energy -4.31633
Interaction Information
Affinity KD=3.6 nM
Affinity_Assay Surface plasmon resonance
PDB_ID None
Type Affinity ligand
Structure
Reference Information
Document_Type Research Articles
Title Searching sequence space for high-affinity binding peptides using ribosome display.
Release_Year 2003
PMID 12758084
DOI 10.1016/S0022-2836(03)00432-7