PPIRE03066
Target Protein Information
| Protein_Name | SaV-like |
|---|---|
| Protein_Sequence | MEDMVDHPPHYNQAGVECIDAIEAALGAENFEFYLQGNVMKYLWRYRYKNGVEDLQKAKWYLEKLIDSTYSP |
| Organism_Source | uncultured virus |
| Functional_Classification | other |
| Cellular_Localization | Extracellular |
| Gene_Names | None |
| UniProt_ID | A0A0A0UXU9 |
| Protein-Protein Interaction Networks | |
Peptide Basic Information
| Peptide_Name | C-6 7G8A |
|---|---|
| Peptide_Sequence | DVEAWLGAR |
| Peptide_Length | 9 |
| Peptide_SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O |
| Chemical_Modification | None |
| Cyclization_Method | None |
| Linear/Cyclic | Linear |
| N-terminal_Modification | Free |
| C-terminal_Modification | Free |
| Amino_Acid_Distribution | |
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Peptide Physicochemical
| Molecular_Weight | 1016.12 |
|---|---|
| Aliphatic_Index | 97.77778 |
| Aromaticity | 0.11111 |
| Average_Rotatable_Bonds | 3.44444 |
| Charge_at_pH_7 | -0.99980 |
| Isoelectric_Point | 4.18441 |
|---|---|
| Number_of_Hydrogen_Bond_Acceptors | 13 |
| Number_of_Hydrogen_Bond_Donors | 16 |
| Topological_Polar_Surface_Area | 448.41000 |
| X_logP_energy | -3.02323 |
Interaction Information
| Affinity | KD=17 nM |
|---|---|
| Affinity_Assay | Surface plasmon resonance |
| PDB_ID | None |
| Type | Affinity ligand |
| Structure | |
Reference Information
| Document_Type | Research Articles |
|---|---|
| Title | Searching sequence space for high-affinity binding peptides using ribosome display. |
| Release_Year | 2003 |
| PMID | 12758084 |
| DOI | 10.1016/S0022-2836(03)00432-7 |