PPIRE05572
Target Protein Information
| Protein_Name | None |
|---|---|
| Protein_Sequence | MKKLALVLGSLLVVGSVASAKEVMPAPTPAPKKVVEYVEKPVIVYRDREVAPAWRPNGSVDVQYRWYGNVENRTPKKEDPASPWLGDNVNAGRLQTLTKVNFTEKQTLEIRTRNYHTLMNPKDSQAADDQVRVRHFYKFGKLGSSKIDVTSRLEYKKNNGDAGRKQAEASVLFDFADYIYSNNFFKADKFGFRLGYQHKWAGHNSGVVGQPFNKGTQDNYFINFESEYTLPWGFSAELNAYNYYNVHNKKFATYNKGNKKSQFYGEIEAYLYQHTPLYKTNNVELSFDFEGGYDPYTWHQYKVVSAKDSNKYEVYMLPTLQVSYKPTDFVKLYAAAGAEYRNWAVTAESKAKNWRWQPTAWAGMKVTF |
| Organism_Source | Fusobacterium nucleatum subsp. nucleatum |
| Functional_Classification | porin |
| Cellular_Localization | Plasma membrane |
| Gene_Names | fomA |
| UniProt_ID | Q47903 |
| Protein-Protein Interaction Networks | |
Peptide Basic Information
| Peptide_Name | YQPVPE |
|---|---|
| Peptide_Sequence | YQPVPE |
| Peptide_Length | 6 |
| Peptide_SMILES | CC(C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)O |
| Chemical_Modification | None |
| Cyclization_Method | None |
| Linear/Cyclic | Linear |
| N-terminal_Modification | Free |
| C-terminal_Modification | Free |
| Amino_Acid_Distribution | |
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Peptide Physicochemical
| Molecular_Weight | 731.80 |
|---|---|
| Aliphatic_Index | 48.33333 |
| Aromaticity | 0.16667 |
| Average_Rotatable_Bonds | 3.00000 |
| Charge_at_pH_7 | -1.00109 |
| Isoelectric_Point | 3.84998 |
|---|---|
| Number_of_Hydrogen_Bond_Acceptors | 10 |
| Number_of_Hydrogen_Bond_Donors | 8 |
| Topological_Polar_Surface_Area | 291.86000 |
| X_logP_energy | -1.43070 |
Interaction Information
| Affinity | Ka=4.30E+06 1/M |
|---|---|
| Affinity_Assay | Surface plasmon resonance |
| PDB_ID | None |
| Type | Affinity ligand |
| Structure | |
Reference Information
| Document_Type | Research Articles |
|---|---|
| Title | Fusobacterium nucleatum envelope protein FomA is immunogenic and binds to the salivary statherin-derived peptide. |
| Release_Year | 2010 |
| PMID | 20008529 |
| DOI | 10.1128/IAI.01224-09 |