PPIRE11472

Target Protein Information
Protein_Name None
Protein_Sequence MLWLGWVKTFILKGGKLLFSEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
Organism_Source Sus scrofa
Functional_Classification calcium-binding proteins
Cellular_Localization Cytoplasm
Gene_Names CALM1
UniProt_ID A0A4X1SUB1
Protein-Protein Interaction Networks
Peptide Basic Information
Peptide_Name Mastoparan X
Peptide_Sequence INWKGAAALAKKIL
Peptide_Length 14
Peptide_SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)O)[C@@H](C)CC
Chemical_Modification None
Cyclization_Method None
Linear/Cyclic Linear
N-terminal_Modification Free
C-terminal_Modification amide
Amino_Acid_Distribution
Peptide Physicochemical
Molecular_Weight 1496.86
Aliphatic_Index 140.00000
Aromaticity 0.07143
Average_Rotatable_Bonds 3.64286
Charge_at_pH_7 2.99710
Isoelectric_Point 11.10307
Number_of_Hydrogen_Bond_Acceptors 19
Number_of_Hydrogen_Bond_Donors 20
Topological_Polar_Surface_Area 578.56000
X_logP_energy -2.41750
Interaction Information
Affinity KD=0.9 nM
Affinity_Assay fluorescence anisotropy
PDB_ID None
Type Inhibitor
Structure
Reference Information
Document_Type Research Articles
Title Construction of a synthetic gene for the metalloregulatory protein MerR and analysis of regionally mutated proteins for transcriptional regulation.
Release_Year 1984
PMID 8155633
DOI 10.1021/bi00180a010