PPIRE11859

Target Protein Information
Protein_Name Signal recognition particle 43 kDa protein, chloroplastic
Protein_Sequence MQKVFLAMDTCALVIHQSLSRIKLSPPKSSSSSSSAFSPESLPIRRIELCFRGAICAAVQRNYEETTSSVEEAEEDDESSSSYGEVNKIIGSRTAGEGAMEYLIEWKDGHSPSWVPSSYIAADVVSEYETPWWTAARKADEQALSQLLEDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELAREILKTTPKGNPMQFGRRIGLEKVINVLEGQVFEYAEVDEIVEKRGKGKDVEYLVRWKDGGDCEWVKGVHVAEDVAKDYEDGLEYAVAESVIGKRVGDDGKTIEYLVKWTDMSDATWEPQDNVDSTLVLLYQQQQPMNE
Organism_Source Arabidopsis thaliana
Functional_Classification signal recognition particle component
Cellular_Localization Cytoplasm
Gene_Names CAO
UniProt_ID O22265
Protein-Protein Interaction Networks
Peptide Basic Information
Peptide_Name A3CT IVp
Peptide_Sequence EVGQRRSKRSKRKRT
Peptide_Length 15
Peptide_SMILES CC(C)[C@H](NC(=O)[C@@H](N)CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)O)[C@@H](C)O
Chemical_Modification None
Cyclization_Method None
Linear/Cyclic Linear
N-terminal_Modification Free
C-terminal_Modification Free
Amino_Acid_Distribution
Peptide Physicochemical
Molecular_Weight 1872.17
Aliphatic_Index 19.33333
Aromaticity 0.00000
Average_Rotatable_Bonds 4.73333
Charge_at_pH_7 6.99886
Isoelectric_Point 12.68998
Number_of_Hydrogen_Bond_Acceptors 29
Number_of_Hydrogen_Bond_Donors 39
Topological_Polar_Surface_Area 999.36000
X_logP_energy -14.32805
Interaction Information
Affinity KD=15 uM
Affinity_Assay Isothermal titration calorimetry
PDB_ID None
Type Affinity ligand
Structure
Reference Information
Document_Type Research Articles
Title Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction.
Release_Year 2015
PMID 26568381
DOI 10.1038/ncomms9875