PPIRE12293

Target Protein Information
Protein_Name None
Protein_Sequence LEYSTSECHFFNGTERVRFLDRYFYNQEEYVRFDSDVGEFRAVTELGRPDEEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFTVQ
Organism_Source Homo sapiens
Functional_Classification Major histocompatibility complex class II
Cellular_Localization Plasma membrane
Gene_Names HLADRB1
UniProt_ID Q07493
Protein-Protein Interaction Networks
Peptide Basic Information
Peptide_Name Human serum albumin 106-120
Peptide_Sequence ETYGEMADCCAKQEPE
Peptide_Length 16
Peptide_SMILES CSCC[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)O
Chemical_Modification None
Cyclization_Method None
Linear/Cyclic Linear
N-terminal_Modification Free
C-terminal_Modification Free
Amino_Acid_Distribution
Peptide Physicochemical
Molecular_Weight 1803.95
Aliphatic_Index 12.50000
Aromaticity 0.06250
Average_Rotatable_Bonds 3.68750
Charge_at_pH_7 -4.11956
Isoelectric_Point 3.67190
Number_of_Hydrogen_Bond_Acceptors 29
Number_of_Hydrogen_Bond_Donors 27
Topological_Polar_Surface_Area 787.10000
X_logP_energy -8.88210
Interaction Information
Affinity IC50=1.41 uM
Affinity_Assay ELISA
PDB_ID None
Type Affinity ligand
Structure
Reference Information
Document_Type Research Articles
Title Purification and characterization of endogenous peptides extracted from HLA-DR isolated from the spleen of a patient with rheumatoid arthritis.
Release_Year 1995
PMID 7539763
DOI 10.1002/eji.1830250553