PPIRE12775
Target Protein Information
| Protein_Name | None |
|---|---|
| Protein_Sequence | YLEQGQNLRMTGHLHHLEPKRVKIIVEEVRLALTEGKLLKMLGSQEPRYLIQLPYVWIEKYPWQPGRSRVPGTSLTSEEKKLIEKKLPDNLPDAKLVSSFEFMELIDFLHKRSQEELPSNHQMPLSEAFAEHIKRRLLYSGTVTRIDSP |
| Organism_Source | Aphanizomenon flos-aquae var. klebahnii |
| Functional_Classification | transcription factor |
| Cellular_Localization | Cytoplasm |
| Gene_Names | hetR |
| UniProt_ID | Q8KXC6 |
| Protein-Protein Interaction Networks | |
Peptide Basic Information
| Peptide_Name | PatS5 |
|---|---|
| Peptide_Sequence | RGSGR |
| Peptide_Length | 5 |
| Peptide_SMILES | N=C(N)NCCC[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H](N)CCCNC(=N)N)C(=O)O |
| Chemical_Modification | None |
| Cyclization_Method | None |
| Linear/Cyclic | Linear |
| N-terminal_Modification | Free |
| C-terminal_Modification | Free |
| Amino_Acid_Distribution | |
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Peptide Physicochemical
| Molecular_Weight | 531.57 |
|---|---|
| Aliphatic_Index | 0.00000 |
| Aromaticity | 0.00000 |
| Average_Rotatable_Bonds | 3.60000 |
| Charge_at_pH_7 | 1.99798 |
| Isoelectric_Point | 12.50011 |
|---|---|
| Number_of_Hydrogen_Bond_Acceptors | 9 |
| Number_of_Hydrogen_Bond_Donors | 13 |
| Topological_Polar_Surface_Area | 323.75000 |
| X_logP_energy | -5.88086 |
Interaction Information
| Affinity | KD=227 nM |
|---|---|
| Affinity_Assay | in vitro binding assay |
| PDB_ID | None |
| Type | Inhibitor |
| Structure | |
Reference Information
| Document_Type | Research Articles |
|---|---|
| Title | Structural insights into HetR-PatS interaction involved in cyanobacterial pattern formation. |
| Release_Year | 2015 |
| PMID | 26576507 |
| DOI | 10.1038/srep16470 |