PPIRE16110

Target Protein Information
Protein_Name Capsid protein
Protein_Sequence MSKRPGDIIISTPVSKVRRRLNFDSPYSSRAAVPIVQGTNKRRSWTYRPMYRKPRIYRMYRSPDVPRGCEGPCKVQSYEQRDDIKHTGIVRCVSDVTRGSGITHRVGKRFCVKSIYFLGKVWMDENIKKQNHTNQVMFFLVRDRRPYGNSPMDFGQVFNMFDNEPSTATVKNDLRDRFQVMRKFHATVIGGPSGMKEQALVKRFFKINSHVTLFIFIQEAAKYENHTENALLLYMACTHASNPVYATMKIRIYFYDSISN
Organism_Source Tomato yellow leaf curl virus (strain Israel)
Functional_Classification coat proteins
Cellular_Localization Cytoplasm
Gene_Names None
UniProt_ID P27256
Protein-Protein Interaction Networks
Peptide Basic Information
Peptide_Name CP-NLS
Peptide_Sequence KRPGDIIISTPVSKVRRR
Peptide_Length 18
Peptide_SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C)C(C)C)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC
Chemical_Modification None
Cyclization_Method None
Linear/Cyclic Linear
N-terminal_Modification Free
C-terminal_Modification Free
Amino_Acid_Distribution
Peptide Physicochemical
Molecular_Weight 2078.49
Aliphatic_Index 97.22222
Aromaticity 0.00000
Average_Rotatable_Bonds 3.88889
Charge_at_pH_7 4.99783
Isoelectric_Point 12.51643
Number_of_Hydrogen_Bond_Acceptors 29
Number_of_Hydrogen_Bond_Donors 35
Topological_Polar_Surface_Area 938.07000
X_logP_energy -10.11482
Interaction Information
Affinity KD=10 nM
Affinity_Assay ELISA
PDB_ID None
Type Affinity ligand
Structure
Reference Information
Document_Type Research Articles
Title Positively charged peptides can interact with each other as revealed by solid phase binding assays
Release_Year 2006
PMID 16581010
DOI 10.1016/j.ab.2006.03.002