PPIRE16111

Target Protein Information
Protein_Name Nuclear shuttle protein
Protein_Sequence MYSTSNRRGRSQTQRGSHVRRTGVKRSYGAARGDDRRRPNVVSKTQVEPRMTIQRVQENQFGPEFVLSQNSALSTFVTYPSYVKTVPNRTRTYIKLKRVRFKGTLKIERGQGDTIMDGPSSNIEGVFSMVIVVDRKPHVSQSGRLHTFDELFGARIHCHGNLSVVPALKDRYYIRHVTKRVVSLEKDTLLIDLHGTTQLSNKRYNCWASFSDLERDSCNGVYGNITKNALLVYYCWLSDAQSKASTYVSFELDYLG
Organism_Source Squash leaf curl virus
Functional_Classification movement proteins
Cellular_Localization Cytoplasm
Gene_Names None
UniProt_ID P21935
Protein-Protein Interaction Networks
Peptide Basic Information
Peptide_Name BV1-NLS
Peptide_Sequence KIEPNRSRSYIKLKRLRFKGTVK
Peptide_Length 23
Peptide_SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCCN)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)O)C(C)C)[C@@H](C)O
Chemical_Modification None
Cyclization_Method None
Linear/Cyclic Linear
N-terminal_Modification Free
C-terminal_Modification Free
Amino_Acid_Distribution
Peptide Physicochemical
Molecular_Weight 2818.41
Aliphatic_Index 80.43478
Aromaticity 0.08696
Average_Rotatable_Bonds 4.39130
Charge_at_pH_7 7.99742
Isoelectric_Point 12.14505
Number_of_Hydrogen_Bond_Acceptors 39
Number_of_Hydrogen_Bond_Donors 46
Topological_Polar_Surface_Area 1233.74000
X_logP_energy -10.96342
Interaction Information
Affinity KD=10 nM
Affinity_Assay ELISA
PDB_ID None
Type Affinity ligand
Structure
Reference Information
Document_Type Research Articles
Title Positively charged peptides can interact with each other as revealed by solid phase binding assays
Release_Year 2006
PMID 16581010
DOI 10.1016/j.ab.2006.03.002