PPIRE16300

Target Protein Information
Protein_Name None
Protein_Sequence MDISLSLVFLVLFIKGVQCEVQLVETGGGLVQPGRSLKLSCVASGFTFSSYWMYWIRQAPGKGLEWVSSINTDGGSTYYPDSVKGRFTISRDNAENTVYLQMNSLRSEDTATYYCAKGGEYYGYNYPFDYWGQGVMVTVSSAETTAPSVYPLAPGTALKSNSMVTLGCLVKGYFPEPVTVTWNSGALSSGVHTFPAVLQSGLYTLTSSVTVPSSTWPSQTVTCNVAHPASSTKVDKKIVPRNCGGDCKPCICTGSEVSSVFIFPPKPKDVLTITLTPKVTCVVVDISQDDPEVHFSWFVDDVEVHTAQTRPPEEQFNSTFRSVSELPILHQDWLNGRTFRCKVTSAAFPSPIEKTISKPEGRTQVPHVYTMSPTKEEMTQNEVSITCMVKGFYPPDIYVEWQMNGQPQENYKNTPPTMDTDGSYFLYSKLNVKKEKWQQGNTFTCSVLHEGLHNHHTEKSLSHSPGK
Organism_Source Rattus norvegicus
Functional_Classification immunoglobulin
Cellular_Localization Extracellular
Gene_Names Ighg
UniProt_ID Q4VBH1
Protein-Protein Interaction Networks
Peptide Basic Information
Peptide_Name MBP12439
Peptide_Sequence QDENPVVHFFKNIVTPRTPPPS
Peptide_Length 22
Peptide_SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](N)CCC(N)=O)C(C)C)C(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)[C@@H](C)O)C(C)C
Chemical_Modification None
Cyclization_Method None
Linear/Cyclic Linear
N-terminal_Modification biotinylation
C-terminal_Modification Free
Amino_Acid_Distribution
Peptide Physicochemical
Molecular_Weight 2519.84
Aliphatic_Index 57.27273
Aromaticity 0.09091
Average_Rotatable_Bonds 3.27273
Charge_at_pH_7 0.09082
Isoelectric_Point 7.55034
Number_of_Hydrogen_Bond_Acceptors 34
Number_of_Hydrogen_Bond_Donors 31
Topological_Polar_Surface_Area 1011.63000
X_logP_energy -9.92263
Interaction Information
Affinity KD=10 nM
Affinity_Assay Surface Plasmon Resonance
PDB_ID None
Type Affinity ligand
Structure
Reference Information
Document_Type Research Articles
Title Liposome-encapsulated peptides protect against experimental allergic encephalitis
Release_Year 2013
PMID 23047895
DOI 10.1096/fj.12-213975