PPIRE16569

Target Protein Information
Protein_Name Ig gamma-2 chain C region
Protein_Sequence SARTTAPSVFPLAASCVDTSGSMMTLGCLVKGYFPEPVTVKWNSGALTSGVHTFPAVLQSGLYSLTSMVTVPSSQKATCNVAHPASSTKVDKTVEPIRTPZPBPCTCPKCPPPENLGGPSVFIFPPKPKDTLMISLTPRVTCVVVDVSQDEPEVQFTWFVDNKPVGNAETKPRVEQYNTTFRVESVLPIQHQDWLRGKEFKCKVYNKALPAPIEKTISKTKGAPRMPDVYTLPPSRDELSKSKVSVTCLIINFFPADIHVEWASNRVPVSEKEYKNTPPIEDADGSYFLYSKLTVDKSAWDQGTVYTCSVMHEALHNHVTQKAISRSPG
Organism_Source Cavia porcellus
Functional_Classification immunoglobulins
Cellular_Localization Extracellular
Gene_Names None
UniProt_ID P01862
Protein-Protein Interaction Networks
Peptide Basic Information
Peptide_Name CCK-12
Peptide_Sequence ISDRDYMGWMDF
Peptide_Length 12
Peptide_SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
Chemical_Modification Y6=sulfotyrosine
Cyclization_Method None
Linear/Cyclic Linear
N-terminal_Modification Free
C-terminal_Modification Amide
Amino_Acid_Distribution
Peptide Physicochemical
Molecular_Weight 1535.71
Aliphatic_Index 32.50000
Aromaticity 0.25000
Average_Rotatable_Bonds 4.00000
Charge_at_pH_7 -2.00153
Isoelectric_Point 3.82610
Number_of_Hydrogen_Bond_Acceptors 21
Number_of_Hydrogen_Bond_Donors 22
Topological_Polar_Surface_Area 613.47000
X_logP_energy -3.49053
Interaction Information
Affinity IC50=1.8 pM
Affinity_Assay ELISA
PDB_ID None
Type Affinity ligand
Structure
Reference Information
Document_Type Research Articles
Title Induction and Detection of Anti-Peptide Antibody Specificity Is Critically Affected by the Mode of Hapten Presentation
Release_Year 1992
PMID 1381185
DOI 10.1515/bchm3.1992.373.1.315