PPIRE16785

Target Protein Information
Protein_Name Ig gamma-2A chain C region A allele
Protein_Sequence AKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPRGPTIKPCPPCKCPAPNLLGGPSVFIFPPKIKDVLMISLSPIVTCVVVDVSEDDPDVQISWFVNNVEVHTAQTQTHREDYNSTLRVVSALPIQHQDWMSGKEFKCKVNNKDLPAPIERTISKPKGSVRAPQVYVLPPPEEEMTKKQVTLTCMVTDFMPEDIYVEWTNNGKTELNYKNTEPVLDSDGSYFMYSKLRVEKKNWVERNSYSCSVVHEGLHNHHTTKSFSRTPGK
Organism_Source Mus musculus
Functional_Classification immunoglobulins
Cellular_Localization Extracellular
Gene_Names Ighg
UniProt_ID P01863
Protein-Protein Interaction Networks
Peptide Basic Information
Peptide_Name Conjugate 17
Peptide_Sequence KDYKDDDDK
Peptide_Length 9
Peptide_SMILES NCCCC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](N)CCCCN)C(=O)O
Chemical_Modification K1(biotinylcaproate); K4(biotinylcaproate); K9(biotinylcaproate)
Cyclization_Method None
Linear/Cyclic Linear
N-terminal_Modification biotinylation
C-terminal_Modification Free
Amino_Acid_Distribution
Peptide Physicochemical
Molecular_Weight 1141.16
Aliphatic_Index 0.00000
Aromaticity 0.11111
Average_Rotatable_Bonds 4.55556
Charge_at_pH_7 -2.00152
Isoelectric_Point 4.15642
Number_of_Hydrogen_Bond_Acceptors 19
Number_of_Hydrogen_Bond_Donors 19
Topological_Polar_Surface_Area 580.91000
X_logP_energy -6.01450
Interaction Information
Affinity KD=13518 nM
Affinity_Assay Surface Plasmon Resonance
PDB_ID None
Type Affinity ligand
Structure
Reference Information
Document_Type Research Articles
Title A Chemoselective Method for Site-Specific Immobilization of Peptides via Aminooxy Group
Release_Year 2001
PMID 11312673
DOI 10.1021/bc0001239