PPIRE16986

Target Protein Information
Protein_Name Ig gamma-1 chain C region secreted form
Protein_Sequence AKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSPRPSETVTCNVAHPASSTKVDKKIVPRDCGCKPCICTVPEVSSVFIFPPKPKDVLTITLTPKVTCVVVDISKDDPEVQFSWFVDDVEVHTAQTQPREEQFNSTFRSVSELPIMHQDWLNGKEFKCRVNSAAFPAPIEKTISKTKGRPKAPQVYTIPPPKEQMAKDKVSLTCMITDFFPEDITVEWQWNGQPAENYKNTQPIMNTNGSYFVYSKLNVQKSNWEAGNTFTCSVLHEGLHNHHTEKSLSHSPGK
Organism_Source Mus musculus
Functional_Classification immunoglobulin receptors
Cellular_Localization Extracellular
Gene_Names Ighg1
UniProt_ID P01868
Protein-Protein Interaction Networks
Peptide Basic Information
Peptide_Name L128S
Peptide_Sequence INNSIVELIRGT
Peptide_Length 12
Peptide_SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@H](C(=O)O)[C@@H](C)O)[C@@H](C)CC)C(C)C)[C@@H](C)CC
Chemical_Modification None
Cyclization_Method None
Linear/Cyclic Linear
N-terminal_Modification Free
C-terminal_Modification Free
Amino_Acid_Distribution
Peptide Physicochemical
Molecular_Weight 1328.53
Aliphatic_Index 154.16667
Aromaticity 0.00000
Average_Rotatable_Bonds 3.75000
Charge_at_pH_7 -0.00024
Isoelectric_Point 6.41015
Number_of_Hydrogen_Bond_Acceptors 19
Number_of_Hydrogen_Bond_Donors 21
Topological_Polar_Surface_Area 609.26000
X_logP_energy -6.54513
Interaction Information
Affinity KD=15.4 nM
Affinity_Assay Surface Plasmon Resonance
PDB_ID None
Type Affinity ligand
Structure
Reference Information
Document_Type Research Articles
Title Epitope analysis using kinetic measurements of antibody binding to synthetic peptides presenting single amino acid substitutions
Release_Year 1993
PMID 7508237
DOI 10.1002/jmr.300060205