PPIRE17215
Target Protein Information
| Protein_Name | None |
|---|---|
| Protein_Sequence | MGPGALFLLLSGTLALTGTQAGPHSLSYFYTAVSRPDRGEPRFIAVGYVDDTQFVRFDNYAPNPRMEPRVPWIQQEGQDYWDEETRKVKDNAQTLRVGLNTLRGYYNQSEAGSHTLQSMFGCYLGPDGLLLHGYRQDAYDGADYIALNEDLRSWTAADMAAQISKRKWEAADEAERMRSYLQGRCVEGLRRYLQMGKDTLQRADPPKTHVTRHPSSDLGVTLRCWALGFYPKEISLTWQREGQDQSQDMELVETRPSGDGTFQKWAALVVPPGEEQSYTCHVQHEGLQEPLTLRWDPAQPPVPMVGITVGLVLVLVAGAMVAGVVIWRKTRSGEKGGSYTQAAGSDSAQGSDVSLTKDPRV |
| Organism_Source | Sus scrofa |
| Functional_Classification | MHC class1 molecules |
| Cellular_Localization | Plasma membrane |
| Gene_Names | SLA1 |
| UniProt_ID | Q9TQ85 |
| Protein-Protein Interaction Networks | |
Peptide Basic Information
| Peptide_Name | SSVGVTHGY |
|---|---|
| Peptide_Sequence | SSVGVTHGY |
| Peptide_Length | 9 |
| Peptide_SMILES | CC(C)[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](N)CO)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@H](C)O |
| Chemical_Modification | None |
| Cyclization_Method | None |
| Linear/Cyclic | Linear |
| N-terminal_Modification | Free |
| C-terminal_Modification | Free |
| Amino_Acid_Distribution | |
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Peptide Physicochemical
| Molecular_Weight | 905.96 |
|---|---|
| Aliphatic_Index | 64.44444 |
| Aromaticity | 0.11111 |
| Average_Rotatable_Bonds | 2.88889 |
| Charge_at_pH_7 | 0.08804 |
| Isoelectric_Point | 7.54235 |
|---|---|
| Number_of_Hydrogen_Bond_Acceptors | 15 |
| Number_of_Hydrogen_Bond_Donors | 15 |
| Topological_Polar_Surface_Area | 405.72000 |
| X_logP_energy | -5.86900 |
Interaction Information
| Affinity | KD=433 nM |
|---|---|
| Affinity_Assay | ELISA |
| PDB_ID | None |
| Type | Affinity ligand |
| Structure | |
Reference Information
| Document_Type | Research Articles |
|---|---|
| Title | Identification of peptides from foot-and-mouth disease virus structural proteins bound by class I swine leukocyte antigen (SLA) alleles SLA-1*0401 and SLA-2*0401 |
| Release_Year | 2012 |
| PMID | 22984928 |
| DOI | 10.1111/j.1365-2052.2012.02400.x |