PPIRE17220

Target Protein Information
Protein_Name None
Protein_Sequence MRVRGPQAILILLSGALALTGTQAGPHSLSYFYTAVSRPDRGDSCFFIVGYVDDTRFVRFDSDAPNAKMEPRAQWIQQEGQEYWDRETQISKDNAQINRVNLNTLRGYYNQSEAGSHTLQRMYGCYLGPDGLLLRGYDQDAYDGADYIALNEDLRSWTAADMAAQISKRKREAADEAEQMRSYLQGRCVEWLQKYLEMGKDTLQRAEPPKTHVTRHSSSDLGVTLRCWALGFYPKEISLSWQREGQDQSQDMELVETRPSGDGTFQKWAALVVPPGEEQSYTCHVQHEGLQEPLTLRWDPAQPPVPMVGIIVGLVLVLVAGAMAAGVVIWRKKRSGEKGGSYTQAAGSDSAQGSDVSLTQDPRV
Organism_Source Sus scrofa
Functional_Classification MHC class1 molecules
Cellular_Localization Plasma membrane
Gene_Names SLA2
UniProt_ID A0A2Z1I809
Protein-Protein Interaction Networks
Peptide Basic Information
Peptide_Name YLSGIAQYY
Peptide_Sequence YLSGIAQYY
Peptide_Length 9
Peptide_SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
Chemical_Modification None
Cyclization_Method None
Linear/Cyclic Linear
N-terminal_Modification Free
C-terminal_Modification Free
Amino_Acid_Distribution
Peptide Physicochemical
Molecular_Weight 1077.20
Aliphatic_Index 97.77778
Aromaticity 0.33333
Average_Rotatable_Bonds 3.44444
Charge_at_pH_7 -0.00457
Isoelectric_Point 6.08020
Number_of_Hydrogen_Bond_Acceptors 15
Number_of_Hydrogen_Bond_Donors 15
Topological_Polar_Surface_Area 420.13000
X_logP_energy -1.87710
Interaction Information
Affinity KD=42 nM
Affinity_Assay ELISA
PDB_ID None
Type Affinity ligand
Structure
Reference Information
Document_Type Research Articles
Title Identification of peptides from foot-and-mouth disease virus structural proteins bound by class I swine leukocyte antigen (SLA) alleles SLA-1*0401 and SLA-2*0401
Release_Year 2012
PMID 22984928
DOI 10.1111/j.1365-2052.2012.02400.x